Results 131 to 140 of about 1,564,685 (307)
, 2019 (A) Phase contrast images of MAYV-infected MDMs over time. Magnification: x20. (B) Phase contrast and fluorescent images of MDMs infected with MAYV preincubated with immune sera.
Sagar B. Kudchodkar (6311873) +16 more
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Opsonophagocytic uptake of KP with sera from conjugate-immunized rabbits.
, 2018 The percent uptake of KP B5055 (O1, circles) or 700603 (O3, squares) inoculum into J774 macrophages was assessed after incubation with pre-immune (grey symbols) or conjugate-induced (black symbols) sera from individual rabbits.
Sharon M. Tennant (225110) +15 more
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DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Dose-dependent protective efficacy of H5N1 vaccine-induced immune sera in mice.
, 2013 Shown are reciprocal MN titers:aexpected titer based on the volume and titer of injected immune sera;bmeasured circulating titer 2 h prior to challenge;cextrapolated from titers measured 2 h prior to challengea.dMice were challenged intranasally with 104
Otfried Kistner (132940) +7 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Enhancing properties of sera from 5–6 weeks old mice born to DENV1-immune mothers.
, 2016 K562 cells were infected with a mixture of DENV2-D2Y98P-PP1 and serially diluted pooled sera from mice born to DENV1-immune mothers (circle) or that from naïve mothers (square). Virus titers in supernatant were determined by plaque assay in BHK cells and
Julia María Martínez Gómez (2577871) +7 more
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Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2005 Although childhood acute lymphoblastic leukemia (ALL) is highly responsive to chemotherapy, reliable techniques are needed to determine treatment outcome. Over expression of 9-O-acetylated sialoglycoconjugates (9-OAcSGs) on lymphoblasts and concomitant
Bhattacharya, Dilip Kumar +5 more
core +1 more source