Results 231 to 240 of about 1,447,984 (298)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Effects of improved water, sanitation, handwashing, and nutrition on early childhood IgG immune repertoire development against <i>Shigella</i> and enteroinvasive <i>Escherichia coli</i> (EIEC). [PDF]

mSphere
Walas N, Kamau E, Zhang M, Kamath K, Reifert J, Shon J, Ali S, Rahman MZ, Shoab AK, Famida SL, Akther S, Hossen MS, Mutsuddi P, Rahman M, Grembi JA, Mertens AN, Bhuiyan TR, Qadri F, Ryan ET, Charles RC, Leung D, Luby S, Lin A, Arnold BF.   +23 more
europepmc   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Rationally Modified SARS-CoV-2 Spike Protein Impairs ACE2 Binding While Preserving Immunogenicity in Mice. [PDF]

Vaccines (Basel)
Tamagnini E, Simonelli L, Palus M, Jost TR, Lazzarini E, Mangani D, Hönig V, Dvořáková M, Arbon D, Gambini F, Lestani S, Grassi F, Barile L, Pedotti M, Sedlacek R, Varani L.   +15 more
europepmc   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Longitudinal assessment of functional antibodies to a novel influenza virus strain across age groups. [PDF]

PLoS Pathog
Huckriede A, Hoorn I, Joshi M, de Vries-Idema J, Vidarsson G, van Kasteren PB, Beukema M.   +6 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Identification of Novel Malaria Antigens Expressed on the Surface of RBCs Infected with <i>Plasmodium falciparum</i>. [PDF]

Vaccines (Basel)
Shakri AR, Mohapatra AD, Badhai J, Anand A, Varghese A, Raj DK.   +5 more
europepmc   +1 more source

GMMA as delivery system for Klebsiella pneumoniae O-antigens and K-antigens. [PDF]

Sci Rep
Raso MM, Nappini R, Gnoni G, Aruta MG, Molfetta M, Arato V, Durante S, Cescutti P, Carducci M, Alfini R, Giannelli C, Rossi O, Pizza M, Micoli F, Gasperini G.   +14 more
europepmc   +1 more source