Results 241 to 250 of about 289,221 (311)

Vaccine-induced antibodies can limit <i>Salmonella</i> infection in the absence of complement or macrophages. [PDF]

mBio
Perez-Toledo M, Aksu-Istil K, Marcial-Juarez E, Persaud RR, Alshayea A, Jossi SE, Carestia A, von Meijenfeld F, Botto M, James LC, Surewaard B, Afzal Z, Shields AM, Horsnell WG, Lopez-Macias C, Henderson IR, OptiVaNTS consortium, Jenne CN, Cunningham AF.   +18 more
europepmc   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Impaired neutralizing antibody responses against the BA1.1, BA.2, and BA.5 Omicron SARS-CoV-2 subvariants in hospitalized adults infected with pre-Omicron variants in Argentina. [PDF]

Microbiol Spectr
Sachithanandham J, Sitaras IA, Albertini RA, Capra RH, Marquez J, Sadino-Vallve GB, Gargantini PR, Cortes PR, Ponce NE, van de Guchte A, Gonzalez-Reiche AS, Olivero NB, Zappia VE, Hernandez-Morfa M, Echenique-Nunez A, Nunez-Fernandez M, Raya-Plasencia L, van Bakel H, Pekosz A, Perez DR, Echenique J.   +20 more
europepmc   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Protective immunity against Chagas disease induced by a superantigen-based chimeric DNA vaccine delivered by attenuated <i>Salmonella</i>. [PDF]

Front Immunol
Antonoglou MB, Sánchez Alberti A, Redolfi DM, Bivona AE, Noli Truant S, Sarratea MB, Cardoso A, Motta FN, Malchiodi EL, Fernández MM.   +9 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Broad and robust T cell immunity compensates the population immune barrier against antibody-escaping Omicron variants. [PDF]

Front Immunol
Guo Y, Guo P, Tian J, Tuluhongtayi Y, Song R, Gao GF, Zhao X, Liu J.   +7 more
europepmc   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source