Results 51 to 60 of about 289,221 (311)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis

Frontiers in Immunology, 2018
A Phase 1b/2a clinical trial of NDV-3A vaccine containing a Candida albicans recombinant Als3 protein formulated with alum protected women <40 years old from recurrent vulvovaginal candidiasis (RVVC).
Priya Uppuluri, Priya Uppuluri, Shakti Singh, Abdullah Alqarihi, Clint S. Schmidt, John P. Hennessey, Michael R. Yeaman, Michael R. Yeaman, Scott G. Filler, Scott G. Filler, John E. Edwards, John E. Edwards, Ashraf S. Ibrahim, Ashraf S. Ibrahim   +13 more
doaj   +1 more source

Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins

BMC Immunology, 2021
Background The natural antibody responses to B-cell epitopes from dengue structural proteins were assessed using immune sera from people having well-defined past dengue infections with one of the four serotypes.
Mahesha N. Nadugala, Chandima Jeewandara, Ramesh S. Jadi, Gathsaurie N. Malavige, Aravinda M. de Silva, Prasad H. Premaratne, Charitha L. Goonasekara   +6 more
doaj   +1 more source

ON CROSS REACTIONS OF IMMUNE SERA TO AZOPROTEINS [PDF]

Journal of Experimental Medicine, 1936
Azoproteins have been prepared with azocomponents possessing two serologically active groups. On immunization with such antigens immune sera were obtained containing two separate, unrelated antibodies, each specific for one of the two groups and separable by absorption.
K, Landsteiner, J, van der Scheer
openaire   +3 more sources

Immune Response induced by RNA-Immuno-carrier extracted from Heterologous Immune Sera [PDF]

Nature, 1965
THE importance of nucleoproteins in antibody-globulin production is well known1,2. In previous experiments3,4 an evident increase of the content of RNA in the γ-globulin fraction in immune sera has been observed. The RNA extracted from the serum of immunized rabbits is capable of eliciting in normal rabbits the production of antibodies against the same
L, MICHELAZZI, I, BALDINI, A, NOVELLI, G, NANNI   +3 more
openaire   +2 more sources

COMPARATIVE CHARACTERISTIC'S OF IMMUNE STATUS OF PAT I ENTS WITH CHRONIC FORMS OF VIRAL HEPATITIS В, C, D AND HEALTHY INDIVIDUALS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Evaluate immune status in patients with chronic hepatitis (CH) depending on type of causative agent and severity of the infectious process. Materials and methods.
S. I. Semenov, A. I. Fedorov, S. S. Maksimova, K. M. Stepanov, F. A. Platonov   +4 more
doaj   +1 more source

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex [PDF]

, 2017
Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health.
Adler, Stuart P., An, Zhiqiang, DePhillips, Pete A., Freed, Daniel C., Fu, Tong-Ming, Ha, Sha, Hamm, Melissa, Li, Fengsheng, Loughney, John W., McLellan, Jason S., McVoy, Michael A., Nickle, David C., Rustandi, Richard R., Tang, Aimin, Troutman, Matthew C., Vlasak, Josef, Wang, Dai, Wang, I-Ming, Zhang, Ningyan, Zhu, Hua   +19 more
core   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

A 53 KDa Glycan Antigen of Hydatid Cyst Wall May Involve in Evasion from Host Immune System

Advanced Biomedical Research, 2018
Background: Recent studies have shown that similar host glycan antigens are expressed by helminths such as Echinococcus granulosus hydatid cysts to evade from host immune system.
Raheleh Rafiei Sefiddashti, Seyedeh Maryam Sharafi, Soltan Ahmad Ebrahimi, Lame Akhlaghi, Ali Moosavi, Abasali Eskandarian, Hossein Yousofi Darani   +6 more
doaj   +1 more source

Evidence for a regulatory idiotypic network in the in vivo response to H-2 antigens. [PDF]

, 1985
Treatment of BALB/c mice with purified pig antiidiotype to 11-4.1 (anti-H-2Kk) monoclonal antibody has been found previously to induce the appearance of idiotype-bearing molecules (Id') in the serum of these mice, in the absence of detectable antigen ...
Bluestone, JA, Rabinowitz, R, Sachs, DH
core