Results 151 to 160 of about 26,342,104 (415)
Role of Vitamin A in the Immune System
Journal of Clinical Medicine, 2018 Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body.
Zhiyi Huang +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
Shift in Nomenclature not Thesis: Innate Immune Memory, Pathogen Dose and Opsonins [PDF]
arXiv, 2018 Recent writings on "innate immune memory" or "trained immunity," and on "hormetic responses," herald reinvigoration of an important research area with early 20th century roots. However, it is questionable that the thesis of a "major importance of the sensed dose of pathogen for the development of innate immune system-mediated responses," should be ...
arxiv
Evolution of the immune system in humans from infancy to old age
Proceedings of the Royal Society B: Biological Sciences, 2015 This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age.
Anna Katharina Simon +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Experimenting with Innate Immunity [PDF]
Proceedings of the Workshop on Artificial Immune Systems and
Immune System Modelling (AISB06), Bristol, UK, p 18-19, 2006, 2010 In a previous paper the authors argued the case for incorporating ideas from innate immunity into artificial immune systems (AISs) and presented an outline for a conceptual framework for such systems. A number of key general properties observed in the biological innate and adaptive immune systems were highlighted, and how such properties might be ...
arxiv
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
The Dynamics of the Skin’s Immune System
International Journal of Molecular Sciences, 2019 The skin is a complex organ that has devised numerous strategies, such as physical, chemical, and microbiological barriers, to protect the host from external insults.
Alan V Nguyen, A. Soulika
semanticscholar +1 more source