Results 101 to 110 of about 21,866,651 (305)

NIOSH Immune, Infectious and Dermal Disease Prevention Program [PDF]

open access: yes
"The National Institute for Occupational Safety and Health (NIOSH) Immune, Infectious and Dermal Disease Prevention Program works with partners in industry, labor, trade associations, professional organizations, and academia. The program focuses on these

core   +1 more source

Leprosy and Immune System An Insight into the Innate Immune System [PDF]

open access: yes, 2021
Innate immunity is a host immune mechanism to defend itself promptly. It includes physical and chemical barriers, cells in the circulation and tissues, several plasma proteins, and immune cells constituting phagocytic cells (monocytes/macrophages and ...
Budiamal, S   +2 more
core  

Impaired telomere integrity and rRNA biogenesis in PARN‐deficient patients and knock‐out models

open access: yesEMBO Molecular Medicine, 2019
PARN, poly(A)‐specific ribonuclease, regulates the turnover of mRNAs and the maturation and stabilization of the hTR RNA component of telomerase. Biallelic PARN mutations were associated with Høyeraal–Hreidarsson (HH) syndrome, a rare telomere biology ...
Maname Benyelles   +14 more
doaj   +1 more source

Glucocorticoid use as a cause of non-cellular immune response to SARS-Cov2 Spike in patients with immune system diseases. [PDF]

open access: yesJ Autoimmun, 2022
Renaudineau Y   +10 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Disturbed Systemic Immune Balance in Periodontal Disease

open access: yesAutoimmunity, 1998
To the editorSir; Human periodontitis is a disease caused by some bacterial infections. In etiopathogene-sis, the role of disturbed local and systemic immunoregulatory mechanisms have drawn the attention. Down-regulation of local T-suppressor cells was commented as the cause of enhanced local immunoglobulin production (1).
Karaarslan, F   +3 more
openaire   +2 more sources

No, vaccine side effects don’t tell you how well your immune system will protect you from COVID-19

open access: yes, 2021
It's normal for different people to mount stronger or weaker immune responses to a vaccine, but post-shot side effects won't tell you which you are. Robert Finberg is a physician who specializes in infectious diseases and immunology at the Medical School
Finberg, Robert W.
core  

The immune system as drug target [PDF]

open access: yes, 2013
The immune system is perhaps the largest yet most diffuse and distributed somatic system in vertebrates. It plays vital roles in fighting infection and in the homeostatic control of chronic disease.
Flower, Darren R.
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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