Results 171 to 180 of about 280,275 (267)

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

open access: yesAdvanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton   +17 more
wiley   +1 more source

Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms

open access: yesAdvanced Materials, EarlyView.
This review describes the driving forces behind collective motion, explores the self‐organization of micro/nano swarms across zero‐dimensional (0D), one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) spaces, and highlights their potential in drug delivery, environmental monitoring, and smart devices.
Siwen Sun   +4 more
wiley   +1 more source

Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual‐Stage Morphing and Drug Release

open access: yesAdvanced Materials, EarlyView.
A 3D‐printed BSA–PEGDA bilayer actuator performs biochemical logic, bending autonomously in acid and releasing its drug payload only when both acid and pepsin are present. This dual‐stage, enzyme‐gated mechanism enables autonomous catch‐and‐release motion and controlled gastric drug delivery, representing a programmable soft material powered by ...
Yuchen Liu   +3 more
wiley   +1 more source

Cross-talk between aging resilience pathways and autoimmunity onset. [PDF]

open access: yesFront Immunol
Mittal R   +3 more
europepmc   +1 more source

Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation

open access: yesAdvanced Materials, EarlyView.
Liquid metal‐based microrobots combine magnetic steering, intrinsic X‐ray visibility and softness, to navigate blood vessels even against flow. Under clinically relevant magnetic fields, liquid metal microrobots roll along vessel walls, cross endothelial barriers, and accumulate in target tissues.
Xiaohui Ju   +7 more
wiley   +1 more source

Multiscale information processing in the immune system. [PDF]

open access: yesFront Immunol
Navarro Quiroz R   +10 more
europepmc   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

open access: yesAdvanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko   +16 more
wiley   +1 more source

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