Results 21 to 30 of about 95,631 (226)

Evolutionary paradigm in cancer immunology*

ESAIM: Proceedings and Surveys, 2014
The dynamical system theory in combination with experimental medical data can serve to improve our understanding of how the immune system works and fights the cancer.
Tsygvintsev Alexei
doaj   +1 more source

The promising roles of macrophages in geriatric hip fracture

Frontiers in Cell and Developmental Biology, 2022
As aging becomes a global burden, the incidence of hip fracture (HF), which is the most common fracture in the elderly population and can be fatal, is rapidly increasing, and its extremely high fatality rate places significant medical and financial ...
Yi-ning Lu, Yi-ning Lu, Ling Wang, Ling Wang, Ying-ze Zhang, Ying-ze Zhang   +5 more
doaj   +1 more source

Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm. [PDF]

PLoS ONE, 2011
Peptide vaccination in cancer therapy is a promising alternative to conventional methods. However, the parameters for this personalized treatment are difficult to access experimentally.
Anna Lena Woelke, Joachim von Eichborn, Manuela S Murgueitio, Catherine L Worth, Filippo Castiglione, Robert Preissner   +5 more
doaj   +1 more source

Selectable diffusion direction with topologically protected edge modes

Communications Physics, 2023
Topological insulators provide great potential to control diffusion phenomena as well as waves. In addition to the thermal localization and robust decay as reported, the topological edge states with higher degree of freedom offers a route to control ...
Keita Funayama, Jun Hirotani, Atsushi Miura, Hiroya Tanaka   +3 more
doaj   +1 more source

Association between Immunosenescence, Mitochondrial Dysfunction and Frailty Syndrome in Older Adults

Cells, 2022
Aging is associated with changes in the immune system, increased inflammation and mitochondrial dysfunction. The relationship between these phenomena and the clinical phenotype of frailty is unclear.
Ilaria Buondonno, Francesca Sassi, Francesco Cattaneo, Patrizia D’Amelio   +3 more
doaj   +1 more source

Influence of Oxidative Stress-Mediated Inflammation on the Pathogenesis of Reproductive Disorders: Exploring the Benefits of Carnosine for Prevention and Treatment of Endometriosis

Frontiers in Bioscience-Landmark
Endometriosis is a chronic pathological condition characterized by the growth of endometrial-like tissue outside the uterine cavity and is frequently associated with severe pain, persistent inflammation, and fibrosis within the pelvic region and other ...
Giuseppe Carota, Lucia Di Pietro, Konstantinos Partsinevelos, Saviana Antonella Barbati, Vincenzo Cardaci, Andrea Graziani, Renata Mangione, Giuseppe Lazzarino, Barbara Tavazzi, Valentina Di Pietro, Emiliano Maiani, Francesco Bellia, Angela Maria Amorini, Giacomo Lazzarino, Giuseppe Caruso   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Immune reactivity features in post-burn dynamics

RUDN Journal of Medicine, 2022
Relevance. To date, burn injury remains a complex type of damage to skin tissues. Along with local destructive and dystrophic phenomena, systemic changes in the body are observed.
Alfiya K. Azhikova, A. L. Yasenyavskaya, M. A. Samotrueva   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning

Frontiers in Genetics
BackgroundCOVID-19 progression and recovery involve complex gene expression changes and immune dysregulation, but their dynamic alterations remain poorly understood.
Zhiyuan Gong, He An
doaj   +1 more source