Results 31 to 40 of about 929,863 (265)
BMC Bioinformatics, 2019 Tuberculosis (TB) represents a worldwide cause of mortality (it infects one third of the world’s population) affecting mostly developing countries, including India, and recently also developed ones due to the increased mobility of the world population ...
M. Pennisi +11 more
semanticscholar +1 more source
Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm. [PDF]
PLoS ONE, 2011 Peptide vaccination in cancer therapy is a promising alternative to conventional methods. However, the parameters for this personalized treatment are difficult to access experimentally.
Anna Lena Woelke +5 more
doaj +1 more source
Immune reactivity features in post-burn dynamics
RUDN Journal of Medicine, 2022 Relevance. To date, burn injury remains a complex type of damage to skin tissues. Along with local destructive and dystrophic phenomena, systemic changes in the body are observed.
Alfiya K. Azhikova +2 more
doaj +1 more source
Aging of the immune system – focus on inflammation and vaccination
European Journal of Immunology, 2016 Major advances in preventing, delaying, or curing individual pathologies are responsible for an increasingly long life span in the developed parts of our planet, and indeed reaching eight to nine decades of life is nowadays extremely frequent.
M. Pinti +8 more
semanticscholar +1 more source
Association between Immunosenescence, Mitochondrial Dysfunction and Frailty Syndrome in Older Adults
Cells, 2022 Aging is associated with changes in the immune system, increased inflammation and mitochondrial dysfunction. The relationship between these phenomena and the clinical phenotype of frailty is unclear.
Ilaria Buondonno +3 more
doaj +1 more source
Frontiers in GeneticsBackgroundCOVID-19 progression and recovery involve complex gene expression changes and immune dysregulation, but their dynamic alterations remain poorly understood.
Zhiyuan Gong, He An
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Frontiers in Bioscience-LandmarkEndometriosis is a chronic pathological condition characterized by the growth of endometrial-like tissue outside the uterine cavity and is frequently associated with severe pain, persistent inflammation, and fibrosis within the pelvic region and other ...
Giuseppe Carota +14 more
doaj +1 more source
Unbalanced Immune System: Immunodeficiencies and Autoimmunity
Frontiers in Pediatrics, 2016 Increased risk of developing autoimmune manifestations has been identified in different primary immunodeficiencies (PIDs). In such conditions, autoimmunity and immune deficiency represent intertwined phenomena that reflect inadequate immune function ...
G. Giardino +12 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source