Results 1 to 10 of about 1,940,460 (362)

COVID-19 vaccination in patients with immune thrombocytopenia

Blood Advances, 2021
Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by low platelet count and increased bleeding risk. COVID-19 vaccination has been described as risk factor for de novo ITP, but the effects of COVID-19 vaccination in ...
Chantal Visser, Maurice Swinkels, E. van Werkhoven, F. N. Croles, H. S. Noordzij-Nooteboom, M. Eefting, Suzanne Last-Koopmans, Cecile A M Idink, P. Westerweel, Bart Santbergen, P. Jobse, F. Baboe, J. Sanders, P. T. te Boekhorst, F. Leebeek, M. Levin, M. Kruip, A. G. Jansen   +17 more
semanticscholar   +1 more source

T cell immune abnormalities in immune thrombocytopenia [PDF]

Journal of Hematology & Oncology, 2014
Immune thrombocytopenia is an autoimmune disease with abnormal T cell immunity. Cytotoxic T cells, abnormal T regulatory cells, helper T cell imbalance, megakaryocyte maturation abnormalities and abnormal T cell anergy are involved in the pathogenesis of this condition.
Ming Hou, Liping Zhang, Jun Peng, Xue-bin Ji   +3 more
openaire   +3 more sources

Bevacizumab-induced immune thrombocytopenia in an ovarian cancer patient with mixed connective tissue disease: case report and literature review

Frontiers in Immunology
Drug-induced immune thrombocytopenia is an adverse reaction marked by accelerated destruction of blood platelets. In cancer therapy, thrombocytopenia has many other causes including bone marrow suppression induced by chemotherapeutic agents, infection ...
Yunting Zhang, Fanchun Yang, Jining Wang, Hui Fu, Fuming Shen, Jie Liu, Dongjie Li   +6 more
doaj   +1 more source

Vaccine-induced thrombosis and thrombocytopenia (VITT); Exploring the unknown

Journal of Family Medicine and Primary Care, 2022
Vaccination is supposed to be the most reliable means to end the COVID 19 pandemic, but recently there have been reports of thrombosis and thrombocytopenia in patients receiving the vaccine especially ChAdOx1 nCoV-19 (AstraZeneca University of Oxford and
Ashok Sunder, Sudip Saha, Sangita Kamath, Manish Kumar   +3 more
doaj   +1 more source

Clinical characteristics, management and outcome of COVID‐19‐associated immune thrombocytopenia: a French multicentre series

British Journal of Haematology, 2020
The causes of secondary immune thrombocytopenia (ITP), which account for approximately 18 to 20% of all adult ITP cases, include some viral infections (Cines et al, 2009; Moulis et al, 2014).
M. Mahévas, G. Moulis, E. Andrès, E. Rivière, M. Garzaro, Étienne Crickx, V. Guillotin, M. Malphettes, L. Galicier, N. Noel, L. Darnige, L. Terriou, C. Guerveno, M. Sanchis-Borja, T. Moulinet, B. Meunier, M. Ebbo, M. Michel, B. Godeau   +18 more
semanticscholar   +1 more source

Rapid onset severe thrombocytopenia following reexposure to piperacillin-tazobactam: report of two cases and review of the literature

Platelets, 2018
Pipercillin-tazobactam is a frequently used antibiotic that has a broad spectrum of antibacterial activity. The development of severe thrombocytopenia following the use of piperacillin-tazobactam is unusual.
Musa Alzahrani, Ibrahim Alrumaih, Fahad Alhamad, Ahmed Abdel Warith   +3 more
doaj   +1 more source

Platelet Activation Mechanisms and Consequences of Immune Thrombocytopenia

Cells, 2021
Autoimmune disorders are often associated with low platelet count or thrombocytopenia. In immune-induced thrombocytopenia (IIT), a common mechanism is increased platelet activity, which can have an increased risk of thrombosis.
Siyu Sun, R. Urbanus, H. ten Cate, P. D. de Groot, B. de Laat, J. Heemskerk, M. Roest   +6 more
semanticscholar   +1 more source

Pathophysiology and Diagnosis of Drug-Induced Immune Thrombocytopenia

Journal of Clinical Medicine, 2020
Drug-induced immune thrombocytopenia (DITP) is a life-threatening clinical syndrome that is under-recognized and difficult to diagnose. Many drugs can cause immune-mediated thrombocytopenia, but the most commonly implicated are abciximab, carbamazepine ...
C. Vayne, E. Guery, J. Rollin, T. Baglo, R. Petermann, Y. Gruel   +5 more
semanticscholar   +1 more source

Management of Adult Patients with Immune Thrombocytopenia (ITP): A Review on Current Guidance and Experience from Clinical Practice

Journal of Blood Medicine, 2021
Immune thrombocytopenia (ITP) is an autoimmune process resulting in increased destruction and inadequate production of platelets that can result in bleeding, fatigue, and reduced health-related quality of life.
Fei Song, Hanny Al‐Samkari
semanticscholar   +1 more source

Secondary immune thrombocytopenia supposedly attributable to COVID-19 vaccination

BMJ Case Reports, 2021
Immune thrombocytopenia (ITP) has been widely reported as a complication of SARS-CoV-2 infection, but to our knowledge, there have been no reports on the association of the COVID-19 vaccine with thrombocytopenia.
Omar Fueyo-Rodríguez, B. Valente-Acosta, R. Jiménez-Soto, Y. Neme-Yunes, S. Inclán-Alarcón, R. Trejo-González, Miguel Ángel García-Salcido   +6 more
semanticscholar   +1 more source