Results 1 to 10 of about 1,952,392 (384)

Thromboembolic events among adult patients with primary immune thrombocytopenia in the United Kingdom General Practice Research Database

Haematologica, 2010
Background The risk of thromboembolic events in adults with primary immune thrombocytopenia has been little investigated despite findings of increased susceptibility in other thrombocytopenic autoimmune conditions.
Ameet Sarpatwari, Dimitri Bennett, John W. Logie, Amit Shukla, Kathleen J. Beach, Adrian C. Newland, Simon Sanderson, Drew Provan   +7 more
doaj   +3 more sources

Success of Helicobacter pylori Eradication Therapy and Long Lasting Platelet Recovery in an Iranian Patient with Severe Immune Thrombocytopenia [PDF]

Journal of Kerman University of Medical Sciences, 2021
Background: Helicobacter pylori is a gram-negative spirochete that usually affects the gastric mucosa and has a prevalence of more than 50% of people worldwide.
Esmaeil Shahabi Satlsar, Maryam Sadat Hosseini, Parisa Taheri, Farahnaz Ghahremanfard, Abbas Ali Imani Fooladi, Mohammad Mosleh   +5 more
doaj   +1 more source

COVID-19-associated immune thrombocytopenia [PDF]

Romanian Journal of Infectious Diseases, 2021
The coronavirus disease 2019 (COVID-19) is a contagious respiratory tract infection caused by the betacoronavirus SARS-CoV-2. The World Health Organization declared the COVID-19 outbreak a pandemic on March 11, 2020.
Mara-Andrada Plesu, Gabriel Cristian Bejan, Ioana Veronica Grajdeanu, Anca Angela Simionescu, Ana Maria Alexandra Stanescu   +4 more
doaj   +1 more source

Acute lower‐extremity arterial thrombosis with immune thrombocytopenia [PDF]

Clinical Case Reports
Key Clinical Message We describe an acute lower‐extremity arterial occlusion in a 30‐year‐old woman with immune thrombocytopenia and polycystic ovary syndrome. Thrombosis may be a complication of immune thrombocytopenia requiring careful management.
Takahiro Nagatomo, Takuya Nagata, Yuju Ohno, Kotaro Numaguchi   +3 more
doaj   +2 more sources

Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis

New England Journal of Medicine, 2021
Background Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a new syndrome associated with the ChAdOx1 nCoV-19 adenoviral vector vaccine against severe acute respiratory syndrome coronavirus 2. Data are lacking on the clinical features of
S. Pavord, M. Scully, B. Hunt, W. Lester, C. Bagot, Brian Craven, Alexandros Rampotas, G. Ambler, M. Makris   +8 more
semanticscholar   +1 more source

Understanding Immune Thrombocytopenia: Looking Out of the Box

Frontiers in Medicine, 2021
The pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP.
Alexandra Schifferli, Alexandra Schifferli, Franco Cavalli, Bertrand Godeau, Howard A. Liebman, Mike Recher, Paul Imbach, Thomas Kühne, Thomas Kühne   +8 more
doaj   +1 more source

How we treat primary immune thrombocytopenia in adults

Journal of Hematology & Oncology, 2023
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder characterized by decreased platelet counts and an increased risk of bleeding.
Xinguang Liu, Yu Hou, M. Hou
semanticscholar   +1 more source

The role of CD8+ T-cell clones in immune thrombocytopenia

Blood, 2023
Key Points • Patients with chronic ITP had clonal expansions of disease-associated TEMRA CD8+ T cells.• CD8+ T cells bind to platelets and cause their activation and apoptosis, defining an antibody-independent mechanism of platelet destruction.
A. Malik, Anwar A. Sayed, P. Han, M. M. Tan, E. Watt, Adela Constantinescu-Bercu, A. Cocker, A. Khoder, Rocel C. Saputil, E. Thorley, Ariam Teklemichael, Yunchuan Ding, A. Hart, Haiyu Zhang, W. Mitchell, N. Imami, J. Crawley, Isabelle I. Salles‐Crawley, J. Bussel, J. Zehnder, S. Adams, Bing M. Zhang, N. Cooper   +22 more
semanticscholar   +1 more source

Treatment of drug-induced immune thrombocytopenias

Haematologica, 2022
Several therapeutic agents can cause thrombocytopenia by either immune-mediated or non-immune-mediated mechanisms. Non-immune-mediated thrombocytopenia is due to direct toxicity of drug molecules to platelets or megakaryocytes.
Irene Marini, Gunalp Uzun, Kinan Jamal, Tamam Bakchoul   +3 more
doaj   +1 more source

Rilzabrutinib, an Oral BTK Inhibitor, in Immune Thrombocytopenia.

New England Journal of Medicine, 2022
BACKGROUND Rilzabrutinib, an oral, reversible covalent inhibitor of Bruton's tyrosine kinase, may increase platelet counts in patients with immune thrombocytopenia by means of dual mechanisms of action: decreased macrophage (Fcγ receptor)-mediated ...
D. Kuter, M. Efraim, J. Mayer, M. Trněný, V. Mcdonald, R. Bird, Thomas Regenbogen, M. Garg, Z. Kaplan, N. Tzvetkov, P. Choi, A. G. Jansen, M. Kostal, R. Baker, J. Gumulec, Eun-Ju Lee, I. Cunningham, Isaac Goncalves, M. Warner, R. Boccia, T. Gernsheimer, W. Ghanima, O. Bandman, R. Burns, A. Neale, Dolca Thomas, P. Arora, Beiyao Zheng, N. Cooper   +28 more
semanticscholar   +1 more source