Haematologica, 2010 Background The risk of thromboembolic events in adults with primary immune thrombocytopenia has been little investigated despite findings of increased susceptibility in other thrombocytopenic autoimmune conditions.
Ameet Sarpatwari +7 more
doaj +3 more sources
Development of thrombocytopenia is associated with improved survival in patients treated with immunotherapy [PDF]
Future Science OA, 2020 Background: Immune-related adverse events are associated with efficacy of immune checkpoint inhibitors (ICIs). We hypothesize that immune-mediated thrombocytopenia could be a biomarker for response to ICIs.
Hussein A Assi +4 more
doaj +3 more sources
Signal detection of immune thrombocytopenia associated with immune checkpoint inhibitors [PDF]
Scientific ReportsImmune checkpoint inhibitors (ICIs) have become an important treatment modality for various malignancies. Due to excessive inflammatory and immune responses, immune-related adverse events (irAEs), such as rash, pruritis, pneumonitis, hepatitis ...
Diwei Mo +6 more
doaj +2 more sources
The Centenary of Immune Thrombocytopenia—Part 2: Revising Diagnostic and Therapeutic Approach [PDF]
Frontiers in Pediatrics, 2017 Primary immune thrombocytopenia (ITP) is the most common cause of thrombocytopenia in children and adolescents and can be considered as a paradigmatic model of autoimmune disease. This second part of our review describes the clinical presentation of ITP,
Rita Consolini +2 more
doaj +4 more sources
Acute lower‐extremity arterial thrombosis with immune thrombocytopenia [PDF]
Clinical Case ReportsKey Clinical Message We describe an acute lower‐extremity arterial occlusion in a 30‐year‐old woman with immune thrombocytopenia and polycystic ovary syndrome. Thrombosis may be a complication of immune thrombocytopenia requiring careful management.
Takahiro Nagatomo +3 more
doaj +2 more sources
Success of Helicobacter pylori Eradication Therapy and Long Lasting Platelet Recovery in an Iranian Patient with Severe Immune Thrombocytopenia [PDF]
Journal of Kerman University of Medical Sciences, 2021 Background: Helicobacter pylori is a gram-negative spirochete that usually affects the gastric mucosa and has a prevalence of more than 50% of people worldwide.
Esmaeil Shahabi Satlsar +5 more
doaj +1 more source
COVID-19-associated immune thrombocytopenia [PDF]
Romanian Journal of Infectious Diseases, 2021 The coronavirus disease 2019 (COVID-19) is a contagious respiratory tract infection caused by the betacoronavirus SARS-CoV-2. The World Health Organization declared the COVID-19 outbreak a pandemic on March 11, 2020.
Mara-Andrada Plesu +4 more
doaj +1 more source
Understanding Immune Thrombocytopenia: Looking Out of the Box
Frontiers in Medicine, 2021 The pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP.
Alexandra Schifferli +8 more
doaj +1 more source
Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis
New England Journal of Medicine, 2021 Background Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a new syndrome associated with the ChAdOx1 nCoV-19 adenoviral vector vaccine against severe acute respiratory syndrome coronavirus 2. Data are lacking on the clinical features of
S. Pavord +8 more
semanticscholar +1 more source
How we treat primary immune thrombocytopenia in adults
Journal of Hematology & Oncology, 2023 Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder characterized by decreased platelet counts and an increased risk of bleeding.
Xinguang Liu, Yu Hou, M. Hou
semanticscholar +1 more source