Results 11 to 20 of about 1,952,392 (384)
Introduction Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count (
J. Bussel+4 more
semanticscholar +5 more sources
T cell immune abnormalities in immune thrombocytopenia [PDF]
Immune thrombocytopenia is an autoimmune disease with abnormal T cell immunity. Cytotoxic T cells, abnormal T regulatory cells, helper T cell imbalance, megakaryocyte maturation abnormalities and abnormal T cell anergy are involved in the pathogenesis of
Jun Peng+3 more
core +5 more sources
Hyperthyroidism and immune thrombocytopenia [PDF]
SummaryHyperthyroidism and immune thrombocytopenia occurred concurrently in five patients; in a sixth, thyrotoxicosis developed after successful treatment of the thrombocytopenia. Correction of the hyperthyroidism was followed by a variable pattern of clinical response.
Peter G. Jacobs+2 more
openalex +4 more sources
Immune thrombocytopenia (ITP) is a common hematologic disorder characterized by isolated thrombocytopenia. ITP presents as a primary or a secondary form. ITP may affect individuals of all ages, with peaks during childhood and in the elderly, in whom the age-specific incidence of ITP is greatest. Bleeding is the most common clinical manifestation of ITP.
Gaurav, Kistangari, Keith R, McCrae
openaire +4 more sources
This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations.
Cooper, Nichola, Ghanima, Waleed Khalid
openaire +3 more sources
Prothrombotic immune thrombocytopenia after COVID-19 vaccination
We report five cases of prothrombotic immune thrombocytopenia after exposure to the ChAdOx1 vaccine (AZD1222, Vaxzevria) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients presented 5 to 11 days after first vaccination.
A. Tiede+11 more
semanticscholar +1 more source
OBJECTIVES:. The development of thrombocytopenia and thrombosis after the administration of the AstraZeneca and Johnson & Johnson/Janssen vaccines has been recently described.
Luca Zazzeron, MD+3 more
doaj +1 more source
Immune thrombocytopenia (ITP) comprises a heterogeneous group of disorders characterized by autoimmune-mediated platelet destruction and impairment of thrombopoiesis. ITP may occur in the absence of an evident predisposing etiology (primary ITP) or secondary to a growing list of associated conditions (secondary ITP), and must be differentiated from ...
Adam, Cuker, Douglas B, Cines
openaire +2 more sources
Chronic primary immune thrombocytopenia (ITP) can today benefit from multiple therapeutic approaches with proven clinical efficacy, including rituximab, thrombopoietin receptor agonists (TPO-RA), and splenectomy.
N. Vianelli+12 more
semanticscholar +1 more source
Background: Platelet count and bleeding risk are frequently used in clinical assessments of the severity of immune thrombocytopenia. On the other hand, immune thrombocytopenia also influences patients’ health-related quality of life.
Dessale Abate Beyene+3 more
doaj +1 more source