Results 21 to 30 of about 1,937,987 (265)

Transjugular intrahepatic portosystemic shunt, local thrombaspiration, and lysis for management of fulminant portomesenteric thrombosis and atraumatic splenic rupture due to vector-vaccine-induced thrombotic thrombocytopenia: a case report

open access: yesJournal of Medical Case Reports, 2022
Introduction Recombinant adenoviral vector vaccines against severe acute respiratory syndrome coronavirus 2 have been observed to be associated with vaccine-induced immune thrombotic thrombocytopenia.
Sandra Emily Stoll   +9 more
doaj   +1 more source

Immune Thrombocytopenia: Recent Advances in Pathogenesis and Treatments

open access: yesHemaSphere, 2021
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to both a peripheral destruction of platelets and an inappropriate bone marrow production.
S. Audia   +5 more
semanticscholar   +1 more source

How I approach new onset thrombocytopenia

open access: yesPlatelets, 2020
Thrombocytopenia is a common reason for referral to hematologists in community and hospital practice. A broad differential diagnosis, combined with the potentially life-threatening nature of some presentations necessitates a rapid evaluation of the ...
Fiona Swain, Robert Bird
doaj   +1 more source

Immune thrombocytopenia

open access: yesExpert Review of Hematology, 2021
Introduction Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count (
J. Bussel   +4 more
semanticscholar   +1 more source

Primary immune thrombocytopenia in children

open access: yesPediatria Polska, 2021
Primary immune thrombocytopenia (ITP) is usually a benign and self-limiting disease in children. Due to the complex pathogenesis involving different immunological processes, its course may be unpredictable.
Agnieszka Książek, Tomasz Szczepański
doaj   +1 more source

Severe, Refractory Immune Thrombocytopenia Occurring After SARS-CoV-2 Vaccine

open access: yesJournal of Blood Medicine, 2021
The rollout of the SARS-CoV-2 vaccine is underway, and millions have already been vaccinated. At least 25 reports of “immune thrombocytopenia” (ITP) or “thrombocytopenia” following the Moderna or Pfizer vaccine have been added to the Vaccine Adverse ...
J. Helms   +6 more
semanticscholar   +1 more source

Exacerbation of immune thrombocytopenia following COVID‐19 vaccination

open access: yesBritish Journal of Haematology, 2021
There is concern that COVID‐19 vaccination may adversely affect immune thrombocytopenia (ITP) patients. Fifty‐two consecutive chronic ITP patients were prospectively followed after COVID‐19 vaccination.
D. Kuter
semanticscholar   +1 more source

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy [PDF]

open access: yes, 2016
Preclinical models suggest that histone deacetylase (HDAC) and mammalian target of rapamycin (mTOR) inhibitors have synergistic anticancer activity. We designed a phase I study to determine the safety, maximum tolerated dose (MTD), recommended phase II ...
et al,, Park, Haeseong
core   +5 more sources

Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection

open access: yesVaccines, 2021
We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration.
Po-Wei Liao   +2 more
doaj   +1 more source

Primary Immune Thrombocytopenia: Novel Insights into Pathophysiology and Disease Management

open access: yesJournal of Clinical Medicine, 2021
Immune thrombocytopenia (ITP) is an autoimmune disorder defined by a significantly reduced number of platelets in blood circulation. Due to low levels of platelets, ITP is associated with frequent bruising and bleeding. Current evidence suggests that low
Anurag Singh, G. Uzun, T. Bakchoul
semanticscholar   +1 more source

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