Results 91 to 100 of about 288,299 (272)
Frontiers in ImmunologyIntroductionRheumatoid arthritis (RA) is an autoimmune disease influenced by genetic factors, particularly HLA-DRB1 alleles. The objective of this study was to characterize the distribution of HLA-DRB1 alleles in Chilean RA patients and healthy controls (
Diego Catalán +11 more
doaj +1 more source
Tolerating Disasters with Hierarchical Consensus [PDF]
IEEE INFOCOM 2024 - IEEE Conference on Computer Communications,
May 2024, Vancouver, France. pp.1241-1250Geo-replication provides disaster recovery after catastrophic accidental failures or attacks, such as fires, blackouts or denial-of-service attacks to a data center or region. Naturally distributed data structures, such as Blockchains, when well designed, are immune against such disruptions, but they also benefit from leveraging locality. In this work,
arxiv +1 more source
Sea squirts and immune tolerance [PDF]
Disease Models & Mechanisms, 2009 Transplantation specificity and protective immunity occur in both adaptive and innate branches of the vertebrate immune system. Understanding the mechanisms that underlie specificity and self-tolerance of immune function has major significance, from preventing a rejection reaction after transplantation to dissecting the causes of autoimmune disease ...
openaire +3 more sources
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Advanced Biology, EarlyView.Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav +5 more
wiley +1 more source
Byzantine Eventual Consistency and the Fundamental Limits of Peer-to-Peer Databases [PDF]
arXiv, 2020 Sybil attacks, in which a large number of adversary-controlled nodes join a network, are a concern for many peer-to-peer database systems, necessitating expensive countermeasures such as proof-of-work. However, there is a category of database applications that are, by design, immune to Sybil attacks because they can tolerate arbitrary numbers of ...
arxiv
Direct Ink Writing of Conductive Hydrogels
Advanced Functional Materials, EarlyView.This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho +6 more
wiley +1 more source
Stochastic approximation to the specific response of the immune system [PDF]
arXiv, 2011 We develop a stochastic model to study the specific response of the immune system. The model is based on the dynamical interaction between Regulatory and Effector CD4+ T cells in the presence of Antigen Presenting Cells inside a lymphatic node. At a mean field level the model predicts the existence of different regimes where active, tolerant, or cyclic
arxiv
Engineering Immune Tolerance with Biomaterials
Advanced Healthcare Materials, 2019 AbstractAutoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory diseases, and immune‐mediated rejection of biologic drugs impact a large number of people across the globe. New understanding of immune function is revealing exciting opportunities to help tackle these challenges by harnessing—or correcting—the specificity of
Joshua M. Gammon, Christopher M. Jewell
openaire +4 more sources
Biofilm Control by Active Topography with Mucin Coating
Advanced Functional Materials, EarlyView.This study reports a new antifouling strategy based on a bioinspired design. Mucin coating enhances biofilm control by active topography with beating micron‐sized pillars. Besides the mechanical force of beating pillars, the antibiofilm activities also involve biological factors since mucin coating inhibits swarming motility and c‐di‐GMP synthesis in ...
Zehui Han +4 more
wiley +1 more source
Carbon Nanotube 3D Integrated Circuits: From Design to Applications
Advanced Functional Materials, EarlyView.As Moore's law approaches its physical limits, carbon nanotube (CNT) 3D integrated circuits (ICs) emerge as a promising alternative due to the miniaturization, high mobility, and low power consumption. CNT 3D ICs in optoelectronics, memory, and monolithic ICs are reviewed while addressing challenges in fabrication, design, and integration.
Han‐Yang Liu +3 more
wiley +1 more source