Results 101 to 110 of about 327,289 (308)

Duality at the gate: Skin dendritic cells as mediators of vaccine immunity and tolerance [PDF]

, 2016
Christopher J. Nirschl, Niroshana Anandasabapathy   +1 more
openalex   +1 more source

TIPE2-modified human amnion-derived mesenchymal stem cells promote the efficacy of allogeneic heart transplantation through inducing immune tolerance [PDF]

, 2021
Feng Wang, Guanping Yao, Sisi Pan, Xin Mao, Xu Zhao, Chuntian Li, Hong Zheng, Guiyou Liang, Limei Yu, Xuanyi Hu, Wanfu Peng   +10 more
openalex   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8+ T cells beneficial in type 1 diabetes

Communications Biology
Distinct Natural Killer (NK)-like CD57+ and PD-1+ CD8+ exhausted-like T cell populations (Tex) have both been linked to beneficial immunotherapy response in autoimmune type 1 diabetes (T1D) patients. The origins and relationships between these cell types
Erin M. Witkop, Kirsten Diggins, Alice Wiedeman, Elisavet Serti, Gerald Nepom, Vivian H. Gersuk, Bryce Fuchs, S. Alice Long, Peter S. Linsley   +8 more
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Blood immunomap for prediction of responses to anti-PD-1 immunotherapy in metastatic non-small cell lung cancer

iScience
Summary: The identification of circulating predictors of response to ICB therapy is vital as very few of them meet the demands of the clinic. Herein, by using high-dimensionality mass cytometry, we designed a blood immunomap in metastatic NSCLC ...
Maria Semitekolou, Nikolaos Paschalidis, Domenico Lo Tartaro, Aikaterini Tsitsopoulou, Panagiota Stamou, Alexandros Mavroudis, Effrosyni Markaki, Athina Varveri, Ioannis Morianos, Matthieu Lavigne, Charalampos Fotsitzoudis, Sofia Magkouta, Konstantina Dede, Ioannis Kalomenidis, Konstantinos Samitas, Konstantinos Potaris, Andrea Cossarizza, Dimitrios Mavroudis, Sara De Biasi, Panayiotis Verginis   +19 more
doaj   +1 more source

Accumulation of LOX-1+ PMN-MDSCs in nasopharyngeal carcinoma survivors with chronic hepatitis B might permit immune tolerance to epstein–barr virus and relate to tumor recurrence

, 2020
Xing Li, Jin‐Long Li, Nan Jiang, Jie Chen, Ziming Liang, Zhenlin Zhao, Yan‐Fang Xing   +6 more
openalex   +2 more sources

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors [PDF]

, 2014
Daniela C. Ifrim, Jessica Quintin, Leo A. B. Joosten, Cor Jacobs, Trees Jansen, Liesbeth Jacobs, Neil A. R. Gow, David L. Williams, J.W.M. van der Meer, Mihai G. Netea   +9 more
openalex   +1 more source

Commentary on IL‐34 deficiency impairs FOXP3⁺ Treg function and decreases immune tolerance homeostasis [PDF]

, 2022
Philippe Saas
openalex   +1 more source