Results 161 to 170 of about 288,299 (272)

Autoimmunity in Reproductive Health and Pregnancy

Journal of Immunology Research, 2018
Jacek Tabarkiewicz, Senthamil R. Selvan, Nathalie Cools   +2 more
doaj   +1 more source

The role of complement in tumor immune tolerance and drug resistance: a double-edged sword. [PDF]

Front Immunol
Yang R, Fu D, Liao A.
europepmc   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune tolerance. [PDF]

Mol Metab
Stüve P, Godoy GJ, Ferreyra FN, Hellriegel F, Boukhallouk F, Kao YS, More TH, Matthies AM, Akimova T, Abraham WR, Kaever V, Schmitz I, Hiller K, Lochner M, Salomon BL, Beier UH, Rehli M, Sparwasser T, Berod L.   +18 more
europepmc   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Restoring immune tolerance in pre-RA: immunometabolic dialogue between gut microbiota and regulatory T cells. [PDF]

Front Immunol
Gao A, Wu R, Mu Y, Jin R, Jiang S, Gao C, Li X, Wang C.   +7 more
europepmc   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

Advanced Science, EarlyView.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang, Qingqing Feng, Chuanming Zheng, Yuanqiang Li, Xinyang Ge, Tiefeng Jin, Gaofeng Hu, Zhuo Tan, Jiafeng Wang, Jiajie Xu, Liehao Jiang, Dan Wang, Zhangguo Ying, Xiao Zhao, Keman Cheng, Qinglin Li, Minghua Ge   +16 more
wiley   +1 more source

Tracing the evolutionary pathway of IgG4: Implications for immune tolerance and regulation. [PDF]

Allergy
Babayev H, Sahin A, Ardicli S, Akdis M, Akdis CA.   +4 more
europepmc   +1 more source

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

Advanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy, Bo Zhao, Ajda Lenardič, Huyen Thuc Tran Luong, Ori Bar‐Nur, Johan Auwerx, Martin Wohlwend   +6 more
wiley   +1 more source

Extracellular vesicles in fetal-maternal immune tolerance. [PDF]

Biomed J
Burlingham WJ.
europepmc   +1 more source