Results 201 to 210 of about 369,026 (262)

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Global trends of peripheral immune tolerance research: a bibliometric and visualization analysis. [PDF]

Front Immunol
Kong S, Lin C, Shen Y, Chen J.
europepmc   +1 more source

The 2025 Nobel Prize in Physiology or Medicine - a bridge to peripheral immune tolerance. [PDF]

J Clin Invest
Bluestone JA.
europepmc   +1 more source

Why Did Treg and Immune Tolerance Win Nobel Prize This Year? [PDF]

Genomics Proteomics Bioinformatics
Zheng 郑颂国 SG.
europepmc   +1 more source

The Follicular Immune Checkpoint: PD-1/PD-L1 and Immune Tolerance in Oocyte Competence and IVF Failure. [PDF]

Int J Mol Sci
Voros C, Christodoulaki C, Petrakou I, Panagopoulou R, Zouganeli I, Sioutis D, Chatzinikolaou F, Papadimas G, Daskalakis G, Panagopoulos P.   +9 more
europepmc   +1 more source

Innate Immune Tolerance Regulates Microglia Response to Aβ Oligomers. [PDF]

J Neurochem
Valerio RR, Santos ÁR, Nóbrega AHL, Martins R, De Felice FG, Ferreira ST, Savino W, Bonomo A, Bernardi A, Frozza RL.   +9 more
europepmc   +1 more source

Hyperglycemia- induced innate immune tolerance involves the metabolic and epigenetic rewiring in human alveolar macrophages. [PDF]

Front Immunol
Wang J, Yuan N, Wang B, Qiu Y, Wang B, Xie L.   +5 more
europepmc   +1 more source

Advancements in Immune Tolerance [PDF]

Advanced Drug Delivery Reviews, 2008
In recent years, considerable attention has been given to immune tolerance and its potential clinical applications for the treatment of cancers and autoimmune diseases, and the prevention of allo-graft rejection and graft-versus-host diseases. Advances in our understanding of the underlying mechanisms of establishment and maintenance of immune ...
Ping-Ying Pan, Zuping Zhou, Shu-Hsia Chen   +2 more
exaly   +3 more sources

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Macroautophagy in Immunity and Tolerance

Traffic, 2009
Autophagy and proteasomal degradation constitute the two main catabolic pathways in cells. While the proteasome degrades primarily short‐lived soluble proteins, macroautophagy, the main constitutive autophagic pathway, delivers cell organelles and protein aggregates for lysosomal degradation.
Gannagé, M, Münz, C
openaire   +4 more sources