Results 201 to 210 of about 637,893 (254)

Macroautophagy in Immunity and Tolerance

Traffic, 2009
Autophagy and proteasomal degradation constitute the two main catabolic pathways in cells. While the proteasome degrades primarily short‐lived soluble proteins, macroautophagy, the main constitutive autophagic pathway, delivers cell organelles and protein aggregates for lysosomal degradation.
Gannagé, M, Münz, C
openaire   +3 more sources

Autophagy and Immune Tolerance

2019
The immune system plays a critical role in defense against invading pathogens, and its function must be strictly controlled to maintain intracellular homeostasis. Once suffering microbial invasion or receiving danger signals, the immune system initiates the responses timely.
Yao-Xing, Wu, Shou-Heng, Jin, Jun, Cui
openaire   +2 more sources

Bile acids for immune tolerance

Science Signaling, 2021
The bacterial bile acid metabolite isoalloLCA stimulates the differentiation of T reg cells.
openaire   +2 more sources

Metabolic reinvigoration of immune tolerance

Nature Reviews Rheumatology, 2021
New research shows that metabolic modulation can restore immune tolerance induction by anti-CD45RB antibodies in lupus-prone mice and reduce systemic lupus erythematosus-like pathology.
openaire   +2 more sources

Immune tolerance in allergy

Current Opinion in Immunology, 2009
Research on the mechanisms of immune regulation in allergy and asthma has shown substantial progress in recent years and has led to a variety of allergen-specific therapeutic and preventive approaches. Studies on the area of allergen-specific immunotherapy (allergen-SIT) have provided substantial knowledge on the mechanisms of allergic disease with ...
openaire   +3 more sources

Gut Immune Tolerance

Science Signaling, 2014
Myeloid cells, innate lymphoid cells, and the cytokines they secrete cooperate to maintain immune tolerance in the gut.
openaire   +2 more sources

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