Results 211 to 220 of about 344,792 (261)
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Tolerance and immune regulation
Immunology Today, 1991Understanding of both the phenomenon of immunological tolerance and the mechanisms by which it is achieved is rapidly advancing, as was evident from a recent meeting. This report summarizes key developments in both T- and B-cell biology.
Robey, Ellen, Urbain, Jacques
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Autophagy and Immune Tolerance
2019The immune system plays a critical role in defense against invading pathogens, and its function must be strictly controlled to maintain intracellular homeostasis. Once suffering microbial invasion or receiving danger signals, the immune system initiates the responses timely.
Yao-Xing, Wu, Shou-Heng, Jin, Jun, Cui
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Current Opinion in Immunology, 2009
Research on the mechanisms of immune regulation in allergy and asthma has shown substantial progress in recent years and has led to a variety of allergen-specific therapeutic and preventive approaches. Studies on the area of allergen-specific immunotherapy (allergen-SIT) have provided substantial knowledge on the mechanisms of allergic disease with ...
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Research on the mechanisms of immune regulation in allergy and asthma has shown substantial progress in recent years and has led to a variety of allergen-specific therapeutic and preventive approaches. Studies on the area of allergen-specific immunotherapy (allergen-SIT) have provided substantial knowledge on the mechanisms of allergic disease with ...
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Tolerance and Immunity in the Intestinal Immune System
Critical Reviews™ in Immunology, 2000The intestinal immune system must guard the body against invasion by pathogens while avoiding a response to the many potential antigens present in food. In the absence of the inflammatory stimuli necessary to elicit an immune response, oral administration of soluble protein antigens induces antigen-specific systemic nonresponsiveness.
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Mechanisms of Immune Tolerance to Allergens
2012In allergic diseases, immune responses are induced by normally well-tolerated allergens, which result in chronic inflammation characterized by antibody secretion and T cell activation. For almost 100 years, allergen-specific immunotherapy (allergen-SIT) has been the potentially curative and antigen-specific method for the treatment of allergic diseases.
Fujita, Hiroyuki +3 more
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Metabolic reinvigoration of immune tolerance
Nature Reviews Rheumatology, 2021New research shows that metabolic modulation can restore immune tolerance induction by anti-CD45RB antibodies in lupus-prone mice and reduce systemic lupus erythematosus-like pathology.
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The immune tolerance network and rheumatic disease: Immune tolerance comes to the clinic
Arthritis & Rheumatism, 2001The development of effective, new, biologically based therapies for RA has created real excitement and justifiable optimism in recent years among rheumatologists and among patients with rheumatic diseases. Recent advances in our understanding of the mechanisms of immune activation and immune tolerance provide further cause for optimism.
B, Diamond, J, Bluestone, D, Wofsy
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Bile acids for immune tolerance
Science Signaling, 2021The bacterial bile acid metabolite isoalloLCA stimulates the differentiation of T reg cells.
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Homotransplantation Immunity and Tolerance in the Bullfrog,
The Journal of Immunology, 1959Summary The bullfrog, Rana catesbeiana, is capable of giving a vigorous isoimmune response to skin homografts, both as a larva and as an adult. First-set skin homografts showed the same median survival times (11.8 ± 0.6 to 13.6 ± 1.0 days) at 25°C on animals ranging in age from 2 months to 2 years.
W H, HILDEMANN, R, HAAS
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Therapeutic induction of antigen-specific immune tolerance
Nature Reviews Immunology, 2023FRANCISCO Quintana +2 more
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