Results 211 to 220 of about 1,952,965 (303)

FGF21 induced by endoplasmic reticulum stress maintains medullary thymic epithelial cell function and central immune tolerance. [PDF]

Sci Adv
Masuda Y, Nakayama Y, Shimizu R, Hasegawa H, Konishi M.   +4 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Free Epstein-Barr virus-induced gene 3 functions as an autonomous immunosuppressive cytokine to maintain immune tolerance. [PDF]

Front Immunol
Miao B, Zhang R, Ye Y, Li L, Zheng P, Zheng H, Yang G, Yang P.   +7 more
europepmc   +1 more source

Editorial: Metabolism and Immune Tolerance

Frontiers in Immunology, 2018
Howie, Duncan, Mauro, Claudio
openaire   +3 more sources

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

The dual role of T cells in solid organ transplant rejection and immune tolerance. [PDF]

Front Immunol
Zhang Z, Zhao N, Miao Y, Sun Y, Liu C, Cao N, Liu C, Ding Y, Li J, Li N.   +9 more
europepmc   +1 more source

Recent advances in stem cell immune tolerance

, 2008
Yen, BL;Yen, ML;Liu, KJ;Chiu, CJ
core  

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Erythropoietin receptor on cDC1s dictates immune tolerance. [PDF]

Nature
Zhang X, McGinnis CS, Yu G, Chen S, Zheng P, Schürch CM, Hiam-Galvez KJ, Reticker-Flynn NE, Guo W, Yao W, Qiu J, Muselman A, Linde IL, Hickey JW, Yan H, Tran VM, Qiu W, Brichart-Vernos D, Hirai T, Yu B, An X, Xiao Y, Paidassi H, Scharschmidt TC, Angelo M, Sheppard D, Chi H, Satpathy AT, Way SS, Malissen B, Strober S, Engleman EG.   +31 more
europepmc   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source