Results 81 to 90 of about 327,289 (308)

Peanut-specific IgG subclasses as biomarkers of peanut allergy in LEAP study participants

World Allergy Organization Journal
Antigen-specific IgG2 and IgG3 are rarely measured in food allergy clinical trials despite known function in preventing mast cell and basophil activation.
Carolyn H. Baloh, MD, Noha Lim, Michelle Huffaker, Pooja Patel, Jody Tversky, George Du Toit, MB, BCh, Gideon Lack, MB, BCh, Tanya M. Laidlaw, Donald W. MacGlashan   +8 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

HLA-DRB1 allele distribution in Chilean population: insights into rheumatoid arthritis susceptibility and protection

Frontiers in Immunology
IntroductionRheumatoid arthritis (RA) is an autoimmune disease influenced by genetic factors, particularly HLA-DRB1 alleles. The objective of this study was to characterize the distribution of HLA-DRB1 alleles in Chilean RA patients and healthy controls (
Diego Catalán, Lilian Soto, Lilian Soto, Óscar Neira, María C. Cuéllar-Gutiérrez, Roberto Díaz-Peña, Roberto Díaz-Peña, Octavio Aravena, Eduard Palou, Montserrat Carrascal, Juan C. Aguillón, Jaxaira Maggi   +11 more
doaj   +1 more source

Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance [PDF]

, 2007
N.J. Robertson, Frances A. Brook, Richard L. Gardner, Stephen Cobbold, Herman Waldmann, Paul J. Fairchild   +5 more
openalex   +1 more source

Induction of Immune Tolerance in Islet Transplantation Using Apoptotic Donor Leukocytes [PDF]

, 2021
Naoya Sato, Shigeru Marubashi
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Gut microbial bile and amino acid metabolism associate with peanut oral immunotherapy failure

Nature Communications
Peanut Oral Immunotherapy (POIT) holds promise for remission of peanut allergy, though treatment is protracted and successful in only a subset of patients. Because the gut microbiome has been linked to food allergy, we sought to identify fecal predictors
Mustafa Özçam, Din L. Lin, Chhedi L. Gupta, Allison Li, J. Carlos Gomez, Lisa M. Wheatley, Carolyn H. Baloh, Srinath Sanda, Stacie M. Jones, Susan V. Lynch   +9 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Mechanisms of tolerance induced by transforming growth factor- -treated antigen-presenting cells: CD8 regulatory T cells inhibit the effector phase of the immune response in primed mice through a mechanism involving Fas ligand [PDF]

, 2004
Michele M Kosiewicz
openalex   +1 more source