Results 131 to 140 of about 383 (191)

Optimization of antibody binding by adjusting thermodynamic stability during the maturation of antibody affinities

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Somatic mutations and antibody clone selection occur in B‐cell hyper‐evolution over extremely brief periods of time. Herein, we developed a technique for antibody screening by immunizing alpacas with antigens and observing antibody sequence transitions over time, a method we named Tracking the Evolution of Antibodies over time.
Yoko Akazawa‐Ogawa, Tomonari Matsuda, Norihiko Kiyose, Nobuo Miyazaki, Tetsuo Fukuta, Motoyasu Adachi, Yuji Ito, Yoshihisa Hagihara   +7 more
wiley   +1 more source

Strengthening Primary Health Care for Improved Population Health and Health Equity in Somalia: A Narrative Review

Public Health Challenges, Volume 5, Issue 3, September 2026.
Primary health care (PHC) strengthening is central to improving population health and advancing health equity in Somalia. Fragmented governance, inadequate financing, workforce maldistribution, and limited access for rural and displaced communities undermine PHC performance.
Yusuf Abdullahi Hubow, Ilyas Abdullahi Khalif, Sharmake Gaiye Bashir, Ahmed Mohamed Omar, Narura Omar Mohamed, Ayan Abdullahi Mohammed, Hibo hassan Mohamed, Nour Ahmed Dahir, Aniso Mohamed Abdi, Abas Nor Abdi, Ahmed Abdinasir Abdulle   +10 more
wiley   +1 more source

Pediatric Tuberculosis in North Kivu: The Urgency of a Targeted Response to a Forgotten Childhood Disease

Public Health Challenges, Volume 5, Issue 3, September 2026.
ABSTRACT Pediatric tuberculosis remains a neglected health emergency, particularly in fragile contexts such as North Kivu province in the Democratic Republic of Congo. While more than one million children contract tuberculosis each year worldwide, the majority of cases remain underdiagnosed, resulting in preventable morbidity and mortality.
Germain Cebweru Murhola, Christian Tague, Dujardin Makeda, Joshua Ekouo, Hermann Yokolo, Aymar Akilimali, Criss Koba Mjumbe   +6 more
wiley   +1 more source

Comprehensive Immunisation Among Children Aged 12–23 Months in India—A Multilevel Modelling Analysis From the National Family Health Survey (2015–21)

Public Health Challenges, Volume 5, Issue 3, September 2026.
ABSTRACT Under‐5 child mortality due to vaccine preventable diseases (VPDs) contributes to an estimated burden of ∼5.2 million deaths globally, mostly within low‐ and middle‐income countries (LMICs). Despite ongoing efforts to expand immunisation coverage, gaps in immunisation remain a persistent public health concern, underscoring the need to examine ...
Mansi Malik, Saurav Basu, Siaa Girotra, Satyajit Kundu   +3 more
wiley   +1 more source

Effects of Lactobacillus Alone and in Combination With Saccharomyces as Alternatives to Antibiotics on Performance and Immunity in Laying Hens

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Supplementation with Lactobacillus plantarum alone or combined with Saccharomyces cerevisiae improved laying performance, egg quality, immune response and caecal microbial balance by increasing beneficial lactic acid bacteria and reducing coliforms, demonstrating probiotics as a safe and sustainable alternative to antibiotic growth promoters in ...
Md. Jahangir Alam, Sonia Tabasum Ahmed, Md. Saiful Islam, Mahfuzul Islam, Md. Mahabbat Ali, Sang‐Suk Lee   +5 more
wiley   +1 more source

Global Surgery at the Frontlines of Conflict Zones: Role of Health Diplomacy in the Provision of On‐Site Surgical Care to Children

World Medical &Health Policy, Volume 18, Issue 3, September 2026.
ABSTRACT Confrontational violence still puts catastrophic burdens on children, with 2024 being the highest recorded levels of displacement, malnutrition, injury, and deprivation in contemporary humanitarian history. Children's surgical care is still grossly underrepresented in health responses worldwide in the prevention of avoidable deaths and long ...
Gaurav Chanderprakash Mittal, Vijay Kumar Chattu, Alma Nurtazina, Satya Sudhakara Bhatt, Altay Dyussupov   +4 more
wiley   +1 more source

On Racialized, Gendered, Precarious Work: Struggles of Community Health Workers During the National Health Insurance Pilot Program in the Tshwane District, South Africa

Gender, Work &Organization, Volume 33, Issue 5, Page 1806-1818, September 2026.
ABSTRACT The infrastructure of precarious work is racialized and gendered, affecting disenfranchised Black women who carry the burden of low paid caregiving within the healthcare system. In South Africa, Community Health Workers, predominantly Black women from marginalized communities, have been vital in providing primary healthcare services at home ...
Sivuyisiwe Wonci
wiley   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, Volume 179, Issue 1, Page 54-71, September 2026.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Interventions to Reduce Screen Time in Preschool‐Aged Children: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Obesity Reviews, Volume 27, Issue 9, September 2026.
ABSTRACT Background The impact of interventions aimed at reducing screen use in preschool‐aged children is unclear. This systematic review and meta‐analysis aimed to evaluate interventions to reduce screen time among preschool‐aged children and examine the characteristics of effective interventions.
Meenushree Chandrasekaran, Qiyang Zhang, Natarajan Padmapriya, Ramkumar Aishworiya, Shang Chee Chong, Gayatri Kembhavi, Bryce McLeod, Keri McCrickerd, Jason Chow, Anna Fogel   +9 more
wiley   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source