Results 141 to 150 of about 383 (191)
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, Volume 13, Issue 43, 3 August 2026.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Advanced Science, Volume 13, Issue 46, 17 August 2026.Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun +11 more
wiley +1 more source
Correspondence: Accelerated primary immunisation schedule
Communicable Diseases Intelligence, 1996 openaire +1 more source
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION ABvac40 is an active immunotherapy targeting Aβ40, the main component of cerebrovascular deposition in Alzheimer's disease (AD). A 24‐month randomized, placebo‐controlled phase 2 study (Part A) showed favorable safety and robust immunogenicity, with exploratory signals of clinical efficacy.
María Pascual‐Lucas +15 more
wiley +1 more source
Prescribing competence: The pros and cons of different methods for assessment
British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2429-2442, August 2026.Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman +3 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 8, August 2026.ABSTRACT Low‐ and middle‐income countries (LMIC) continue to bear a high burden of cervical cancer (CC). Women's participation in CC screening is challenging in LMICs, but self‐collection of HPV tests has shown increased participation in controlled trials.
Ginna Fernández‐Deaza +11 more
wiley +1 more source
Clinical &Translational Immunology, Volume 15, Issue 8, 2026.This study compares the humoral and cellular immunogenicity of Dose 3 of Ancestral SARS‐CoV‐2 vaccine in participants with HIV and/or following lung transplantation with healthy controls. We highlight differences along a spectrum of immunocompromise, and the value of SARS‐CoV‐2 vaccination, even in the absence of detectable neutralisation responses ...
David WJ Griffin +15 more
wiley +1 more source
Precision post‐translational modification of PML defines neuroblastoma clinical behaviour
Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.Promyelocytic leukaemia protein (PML) loss is significantly associated with advanced disease stage, metastasis, relapse, therapy resistance, and poor survival in neuroblastoma. Elevated phosphorylation of PML at S518 promotes PML destabilisation and predicts adverse clinical outcomes. The phosphorylated PML (pPML)/PML ratio provides enhanced prognostic
Sreenidhi Mohanvelu +6 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background/Aims Older adults remain highly vulnerable to severe COVID‐19 outcomes due to immunosenescence and comorbidities. Although booster vaccination strategies have reduced hospitalizations and mortality, evidence regarding the effectiveness, safety, and immunogenicity of a second COVID‐19 vaccine booster dose in older adults remains ...
Marieli Thomazini Piske Garcia +2 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background Knowledge, attitudes, and practices (KAP) studies provide essential insight into public awareness, perceptions, and behaviors toward health issues. Hepatitis B virus (HBV) remains a major public health problem in Jordan. Transfusion‐dependent patients are at higher risk of infection due to frequent exposure to blood products.
Nader Alaridah +11 more
wiley +1 more source