Results 211 to 220 of about 871,284 (309)

Editorial: Cellular replacement therapy for diabetes. [PDF]

Cell Transplant
Sakata N, Yoshimatsu G, Kodama S.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Bovine Viral Diarrhea Virus and Vaccine Protection Strategies. [PDF]

Vet Sci
Hu X, Huang J, Cai Y, Zhang W, Cheng Y.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Challenges in the standardization of innate immune status assessment. [PDF]

Front Immunol
Liu Y, Mao T, Chen R, Luo H, Zhang S, Chen F, Shen X, Li W, Liu J, Guan G, Feng Z, Yin Y.   +11 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Comparative Immunomodulatory Profiles of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> HOM2120 and <i>Bifidobacterium longum</i> subsp. <i>longum</i> HOM1190: Insights from Genomics, <i>In Vitro</i>, and <i>In Vivo</i> Studies. [PDF]

J Microbiol Biotechnol
Wang T, Zhang X, Zhao Y, Fan L, Cao Z, Lee S, Lim C, Zhang S.   +7 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Challenges and Prospects in the Development of a Universal SARS-CoV-2 Vaccine. [PDF]

Vaccines (Basel)
Karczmarzyk K, Kęsik-Brodacka M.
europepmc   +1 more source