Results 241 to 250 of about 562,820 (312)

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Hybrid and Vaccine-Induced Immunity Against SARS-CoV-2 in a Cohort of Hospitalized Patients from the Metropolitan Aburrá Valley, Colombia. [PDF]

Vaccines (Basel)
Hernández-Ortiz OH, Naranjo AF, Vélez-Cadavid JJ, De La Rosa G, Gil BA, Moreno AM, Perez-Restrepo LS, Usuga J, Aristizabal-Valencia M, Molina-Saldarriaga F, Sará-Ochoa JE, Betancourt-Rodriguez N, Jaimes F, Osorio JE, Hernández-Ortiz JP.   +14 more
europepmc   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Foot-and-mouth disease virus-like particle mRNA vaccine induces strong humoral and cellular immunity. [PDF]

Appl Microbiol Biotechnol
Liu H, Zhang Y, Mu S, Hou F, Jiang L, Wang Z, Dong H, Mehdi MM, Guo H, Sun S.   +9 more
europepmc   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Spatial instruction of tissue immunity. [PDF]

Immunohorizons
Reina-Campos M.
europepmc   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Flipping the script: Using mucosal immune obstacles to inform vaccine design. [PDF]

PLoS Pathog
Antia A, Ding S.
europepmc   +1 more source

Redox-metabolic circuits as a central regulator of T cell-based immunotherapy. [PDF]

Front Immunol
McPhedran S, Zhao T, Lum JJ.
europepmc   +1 more source

Development and validation of an interpretable prediction model using spatial patterns of tumor-infiltrating lymphocytes in H&E-stained whole-slide images for immune subtyping of lung adenocarcinoma. [PDF]

Front Immunol
Li X, Qin HZ, Wei JY, Wei KL, Huang ZQ.
europepmc   +1 more source