Results 31 to 40 of about 2,437,393 (325)

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

open access: yesNature Communications, 2016
Broadly neutralizing antibodies (bNAbs) are promising as potential therapies targeting HIV-1 but their overall antiviral activity remains to be fully elucidated.
Timothée Bruel   +12 more
doaj   +1 more source

Specific humoral immunity in Osteichthyes

open access: yesCentral European Journal of Immunology, 2018
The fish immune system is extremely complex and has considerable adaptive potential. In Osteichthyes, the system is formed by lymphopoietic organs which are important for the differentiation and maturation of the immune system cells. These organs include
Michał P. Stosik   +2 more
doaj   +1 more source

Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity

open access: yesImmunity, 2020
We conducted a serological study to define correlates of immunity against SARS-CoV-2. Compared to those with mild coronavirus disease 2019 (COVID-19) cases, individuals with severe disease exhibited elevated virus-neutralizing titers and antibodies ...
Tyler J Ripperger   +36 more
semanticscholar   +1 more source

Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity

open access: yesACS Central Science, 2020
Vaccines aim to elicit a robust, yet targeted, immune response. Failure of a vaccine to elicit such a response arises in part from inappropriate temporal control over antigen and adjuvant presentation to the immune system.
Gillie A. Roth   +14 more
semanticscholar   +1 more source

Shaping humoral immunity to vaccines through antigen-displaying nanoparticles.

open access: yesCurrent Opinion in Immunology, 2020
Strategies to qualitatively and quantitatively enhance the humoral response to immunizations with protein and polysaccharide antigens are of broad interest for development of new and more effective vaccines.
D. Irvine, Benjamin J. Read
semanticscholar   +1 more source

Trade-offs between personal immunity and reproduction in the burying beetle, N. vespilloides [PDF]

open access: yes, 2014
We know that parental investment and immune investment are costly processes, but it is unclear which trait will be prioritised when both may be required.
Cotter, Sheena C.   +3 more
core   +2 more sources

Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria

open access: yesNature Immunology, 2020
Plasmodium parasite–specific antibodies are critical for protection against malaria, yet the development of long-lived and effective humoral immunity against Plasmodium takes many years and multiple rounds of infection and cure.
R. Vijay   +17 more
semanticscholar   +1 more source

Humoral Immunity to Hantavirus Infection

open access: yesmSphere, 2020
Hantaviruses are zoonotic pathogens found in parts of Europe, Asia, South America, and North America, which can cause renal and respiratory failure with fatality rates up to 40%. There are currently no FDA-approved vaccines or therapeutics for hantavirus-
Taylor B. Engdahl, James E. Crowe
doaj   +3 more sources

The Immunoglobulins of Cold-Blooded Vertebrates [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Chen   +22 more
core   +2 more sources

Engineered immunogen binding to alum adjuvant enhances humoral immunity

open access: yesNature Medicine, 2020
Adjuvants are central to the efficacy of subunit vaccines. Aluminum hydroxide (alum) is the most commonly used vaccine adjuvant, yet its adjuvanticity is often weak and mechanisms of triggering antibody responses remain poorly understood.
Tyson J. Moyer   +21 more
semanticscholar   +1 more source

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