Results 41 to 50 of about 164,492 (254)

Clinical and Immunological Efficacy of Treating Children with Bronchial Obstruction Associated with Atypical Pathogens

Zdorovʹe Rebenka, 2015
This article provides information about the clinical course of bronchial obstruction caused by intracellular infection, and the impact of intracellular infection on the cellular, humoral and local immunity in children.
M.P. Prokhorova
doaj   +1 more source

Retrospective of International Serological Studies on the Formation and Dynamics of the Humoral Immune Response to SARS-CoV-2: from 2020 to 2021

Acta Biomedica Scientifica, 2021
Last year the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has started. The new coronavirus is highly contagious and causes severe complications.
E. A. Novikova, A. G. Petrova, E. V. Moskaleva, A. S. Vanyarkinа, L. V. Rychkova   +4 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Assessing COVID IGRA and IgG antibodies in healthcare workers post vaccination

Journal of Infection in Developing Countries
Introduction: This study evaluated the durability of humoral and cell-mediated immunity (CMI) post Pfizer vaccination among healthcare workers (HCWs) at a tertiary care center in Lebanon.
Lina Ghandour, Wissam Yaacoub, George F Araj   +2 more
doaj   +1 more source

Characteristics of cellular and humoral immunity parameters in patients with mechanical jaundice, caused by cholangiocarcinoma

Инфекция и иммунитет, 2022
In the modern world, obstructive jaundice caused by developing a malignant disease cholangiocarcinoma, poses a significant medical and social problem in economically developed and in developing countries.
Olga V. Smirnova, B. G. Gubanov, E. V. Kasparov, M. A. Darenskaya, L. I. Kolesnikova, S. N. Kolesnikov   +5 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Five doses of the mRNA vaccination potentially suppress ancestral-strain stimulated SARS-CoV2-specific cellular immunity: a cohort study from the Fukushima vaccination community survey, Japan

Frontiers in Immunology, 2023
The bivalent mRNA vaccine is recommended to address coronavirus disease variants, with additional doses suggested for high-risk groups. However, the effectiveness, optimal frequency, and number of doses remain uncertain.
Yuta Tani, Morihito Takita, Morihito Takita, Masatoshi Wakui, Hiroaki Saito, Hiroaki Saito, Takamitsu Nishiuchi, Tianchen Zhao, Chika Yamamoto, Takeshi Kawamura, Takeshi Kawamura, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Yudai Kaneko, Tatsuhiko Kodama, Ryuzaburo Shinaha, Masaharu Tsubokura, Masaharu Tsubokura, Masaharu Tsubokura   +19 more
doaj   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source