Results 41 to 50 of about 165,275 (255)

Five doses of the mRNA vaccination potentially suppress ancestral-strain stimulated SARS-CoV2-specific cellular immunity: a cohort study from the Fukushima vaccination community survey, Japan

Frontiers in Immunology, 2023
The bivalent mRNA vaccine is recommended to address coronavirus disease variants, with additional doses suggested for high-risk groups. However, the effectiveness, optimal frequency, and number of doses remain uncertain.
Yuta Tani, Morihito Takita, Morihito Takita, Masatoshi Wakui, Hiroaki Saito, Hiroaki Saito, Takamitsu Nishiuchi, Tianchen Zhao, Chika Yamamoto, Takeshi Kawamura, Takeshi Kawamura, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Yudai Kaneko, Tatsuhiko Kodama, Ryuzaburo Shinaha, Masaharu Tsubokura, Masaharu Tsubokura, Masaharu Tsubokura   +19 more
doaj   +1 more source

Humoral Immunity in Polymyositis/Dermatomyositis

Journal of Investigative Dermatology, 1993
Autoantibodies are found in most patients with polymyositis (PM) or dermatomyositis (DM) and 35-40% of these patients have myositis-specific antibodies. Twenty-five to thirty percent have anti-aminoacyl-tRNA synthetases, of which anti-Jo-1, directed at histidyl-tRNA synthetase, is by far the most common.
openaire   +2 more sources

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Editorial: Tuberculosis and humoral immunity

Frontiers in Immunology
Taru S. Dutt, José Alberto Choreño-Parra   +1 more
doaj   +3 more sources

Characteristics of cellular and humoral immunity parameters in patients with mechanical jaundice, caused by cholangiocarcinoma

Инфекция и иммунитет, 2022
In the modern world, obstructive jaundice caused by developing a malignant disease cholangiocarcinoma, poses a significant medical and social problem in economically developed and in developing countries.
Olga V. Smirnova, B. G. Gubanov, E. V. Kasparov, M. A. Darenskaya, L. I. Kolesnikova, S. N. Kolesnikov   +5 more
doaj   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

HUMORAL IMMUNITY TO HUMAN NEOPLASMS [PDF]

Iranian Journal of Public Health, 1974
Using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. Antibody
D. Shadafza, N. Mohagheghpour
doaj   +1 more source

Improved Humoral Immunity and Protection against Influenza Virus Infection with a 3d Porous Biomaterial Vaccine

Advanced Science, 2023
New vaccine platforms that activate humoral immunity and generate neutralizing antibodies are required to combat emerging pathogens, including influenza virus.
Hiromi Miwa, Olivia Q. Antao, Kindra M. Kelly‐Scumpia, Sevana Baghdasarian, Daniel P. Mayer, Lily Shang, Gina M. Sanchez, Maani M. Archang, Philip O. Scumpia, Jason S Weinstein, Dino Di Carlo   +10 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Comparing population-level humoral and cellular immunity to SARS-Cov-2 in Bangalore, India

Scientific Reports
Two types of immunity, humoral and cellular, offer protection against COVID. Humoral protection, contributed by circulating neutralizing antibodies, can provide immediate protection but decays more quickly than cellular immunity and can lose ...
Anup Malani, Jayashree Aiyar, Andrea Sant, Neha Kamran, Manoj Mohanan, Saloni Taneja, Bartek Woda, Wanran Zhao, Anu Acharya   +8 more
doaj   +1 more source