Innate immunity is an evolutionarily conserved host defense system against infections. The fruit fly Drosophila relies solely on innate immunity for infection defense, and the conservation of innate immunity makes Drosophila an ideal model for ...
Shinzo Iwashita +13 more
doaj +1 more source
Assessing optimal target populations for influenza vaccination programmes: an evidence synthesis and modelling study. [PDF]
BACKGROUND: Influenza vaccine policies that maximise health benefit through efficient use of limited resources are needed. Generally, influenza vaccination programmes have targeted individuals 65 y and over and those at risk, according to World Health ...
Baguelin, Marc +5 more
core +3 more sources
African Trypanosomes undermine humoral responses and vaccine development : link with inflammatory responses? [PDF]
African trypanosomosis is a debilitating disease of great medical and socioeconomical importance. It is caused by strictly extracellular protozoan parasites capable of infecting all vertebrate classes including human, livestock, and game animals.
Achcar +160 more
core +1 more source
PTX3 is expressed in terminal lymphatics and shapes their organization and function
IntroductionThe lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express PTX3, an essential component of humoral ...
Andrea Doni +18 more
doaj +1 more source
Interferon Status and Choice of Interferons Inducers in Frequently Ill Children
Literature data on the study of interferon status in children. Own results of the survey group of frequently ill children (FIC) have shown insufficient production of IFN alpha and gamma-IFN, humoral immunity. It was revealed that 66% of the group FIC has
M. S. Savenkovа +5 more
doaj +1 more source
Evaluation of Microparticulate Ovarian Cancer Vaccine via Transdermal Route of Delivery [PDF]
Ovarian cancer is the fifth most commonly occurring malignancy in women, with the highest mortality rate among all the gynecological tumors. Microparticulate vaccine can serve as an immunotherapeutic approach with a promising antigenic delivery system ...
Akalkotkar, Archana +3 more
core +2 more sources
Hybrid immunity induced by vaccination following recovery from SARS-CoV-2 infection is more robust than immunity induced by either infection or vaccination alone.
Kayla A. Holder +4 more
doaj +1 more source
Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. [PDF]
The polio eradication endgame aims to bring transmission of all polioviruses to a halt. To achieve this aim, it is essential to block viral replication in individuals via induction of a robust mucosal immune response. Although it has long been recognized
Anis E +16 more
core +3 more sources
The Humoral Immunity Response of Dog Vaccinated with Oral Sag2 and Parenteral Rabisin and Rabivet Supra92 [PDF]
This research aims to determine whether SAG2 oral vaccine induced antibody response as high as that of parenteral vaccine (Rabisin and Rabivet Supra 92).
Faizah, F. (Faizah) +3 more
core
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source

