Results 171 to 180 of about 2,416,841 (331)
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, EarlyView.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source
Interferons in human inborn errors of disease
mBioInterferons are ubiquitously produced cytokines with diverse cellular functions. IFNs play essential functions in responding to viral infections and tumorigenesis by initiating an interferon-stimulated gene response and triggering the adaptive immune ...
Laurel Stine +2 more
doaj +1 more source
Thermally Induced Gelling Systems Based on Patchy Polymeric Micelles
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.A novel strategy to design thermally induced gelling systems with tunable material properties is reported. Polymeric mixed‐shell micelles displaying multiple thermosensitive patchy domains formed hydrogels by assembling into well‐entangled worm‐like network structures upon heating to body temperature. The patchy micelle design significantly affects the
Binru Han +9 more
wiley +1 more source
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway.
Immunity, 2020 Xuewu Zhang, X. Bai, Zhijian J. Chen
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García +23 more
wiley +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
Advanced Functional Materials, EarlyView.MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee +6 more
wiley +1 more source
BiomoleculesMetabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most common liver disease worldwide in recent years. MASLD commonly presents as simple hepatic steatosis, but ~25% of patients develop liver inflammation, progressive fibrosis, liver cirrhosis and related hepatocellular carcinoma.
Moritz Meyer +3 more
openaire +3 more sources
Scientific ReportsMesenchymal stromal cells (MSCs) are multipotent adult stem cells which possess immunomodulatory and repair capabilities. In this study, we investigated whether MSC therapy could modulate inflammation and lung damage in the lungs of Scnn1b-transgenic ...
Declan F. Doherty +9 more
doaj +1 more source
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity.
Immunity, 2011 T. Kawai, S. Akira
semanticscholar +1 more source