Results 31 to 40 of about 637,260 (296)

Infectious Bronchitis Virus Infection of Chicken: The Essential Role of Mucosal Immunity [PDF]

, 2021
SUMMARY. Infection with either virulent or vaccine strains of infectious bronchitis virus (IBV) elicits a complex interaction of nonspecific, innate, mucosal, cellular, and humoral immunity, thereby mounting an optimal defensive response in chickens ...
Ganapathy, Kannan, Kannan Ganapathy
core   +1 more source

Nasal IgA Provides Protection against Human Influenza Challenge in Volunteers with Low Serum Influenza Antibody Titre

Frontiers in Microbiology, 2017
In spite of there being a number of vaccines, influenza remains a significant global cause of morbidity and mortality. Understanding more about natural and vaccine induced immune protection against influenza infection would help to develop better ...
Victoria M. W. Gould, James N. Francis, Katie J. Anderson, Bertrand Georges, Alethea V. Cope, John S. Tregoning   +5 more
doaj   +1 more source

Mucosal Immunization and Adjuvants [PDF]

, 2014
The goal of the influenza vaccine is to prevent influenza virus infection and control the yearly seasonal epidemic and pandemic. However, the presently available parenteral influenza vaccine induces only systemic humoral immunity, which does not prevent influenza virus infection on the mucosal surface. Secretary IGA antibodies play an important role in
Hasegawa, Hideki, van Reit, Elly, Kida, Hiroshi   +2 more
openaire   +2 more sources

Impact of HIV infection on the frequency and phenotype of Th17 cells in the female genital tract [PDF]

, 2010
Includes bibliographical references (leaves 85-103).T helper (Th) 17 cells have recently been implicated in regulating gut mucosal immunity during HIV infection by sustaining gut mucosal barrier integrity, although they do not respond to HIV directly ...
Salkinder, Amy Leia
core   +1 more source

Alveolar Macrophages: Adaptation to Their Anatomic Niche during and after Inflammation

Cells, 2021
At the early stages of life development, alveoli are colonized by embryonic macrophages, which become resident alveolar macrophages (ResAM) and self-sustain by local division.
Florian Pierre Martin, Cédric Jacqueline, Jeremie Poschmann, Antoine Roquilly   +3 more
doaj   +1 more source

Endoscopic Management of Gastric Varices: Efficacy and Outcomes of Gluing with N-Butyl-2-Cyanoacrylate in a North American Patient Population

Canadian Journal of Gastroenterology, 2008
BACKGROUND: Gastric variceal bleeding is associated with significant morbidity and mortality in patients with portal hypertension. Outside of North America, gastric variceal injection of N-butyl-2-cyanoacrylate has been shown to be safe and effective ...
PJ Belletrutti, J Romagnuolo, RJ Hilsden, F Chen, B Kaplan, J Love, PL Beck   +6 more
doaj   +1 more source

Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function

Frontiers in Immunology, 2022
The studies described here provide an analysis of the pathogenesis of Blau syndrome and thereby the function of NOD2 as seen through the lens of its dysfunction resulting from Blau-associated NOD2 mutations in its nucleotide-binding domain (NBD). As such,
Liming Mao, Liming Mao, Atika Dhar, Guangxun Meng, Guangxun Meng, Guangxun Meng, Ivan Fuss, Kim Montgomery-Recht, Zhiqiong Yang, Qiuyun Xu, Atsushi Kitani, Warren Strober   +11 more
doaj   +1 more source

Innate immunity against HIV: a priority target for HIV prevention research. [PDF]

, 2010
This review summarizes recent advances and current gaps in understanding of innate immunity to human immunodeficiency virus (HIV) infection, and identifies key scientific priorities to enable application of this knowledge to the development of novel ...
PAXTON W, ROMARIS M, LINDBLAD E, DONCEL G, BORROW P, Persephone Borrow, Borrow, P, LEHNER T, DE MAGISTRIS MT, Shattock, Robin J., MEDAGLINI, DONATA, Vyakarnam, Annapurna, PATTERSON S, Annapurna Vyakarnam, POLI G, EUROPRISE WORKING GROUP BOGERS W, KIRCHHOFF F, KELLY C, TOWERS G, SILVESTRI G, DEBRE P, Robin J Shattock, Shattock, RJ, SHATTOCK RJ, Vyakarnam Annapurna, Borrow, Persephone, Borrow Persephone, GOODIER M, null null, SPECK R, EUROPRISE Working Group, GEIJTENBEEK T, Vyakarnam, A, Shattock Robin J, WAGNER H., VYAKARNAM A   +35 more
core   +1 more source

Age-Stratified T Cell Responses in Children Infected with Mycobacterium tuberculosis

Frontiers in Immunology, 2017
Tuberculosis (TB) in young children differs from adult TB in that the risk of rapid progression to active TB (aTB) is higher in children than in adults. The reasons for this increased risk are not fully understood. Early differentiation remains difficult
Alexandra Dreesman, Véronique Corbière, Violette Dirix, Kaat Smits, Sara Debulpaep, Sara Debulpaep, Iris De Schutter, Myriam Libin, Mahavir Singh, Anne Malfroot, Camille Locht, Camille Locht, Camille Locht, Camille Locht, Françoise Mascart, Françoise Mascart   +15 more
doaj   +1 more source

Mucosal immunity to poliovirus

Expert Review of Vaccines, 2011
The Global Polio Eradication Initiative (GPEI) currently based on use of oral poliovirus vaccine (OPV) has identified suboptimal immunogenicity of this vaccine as a major impediment to eradication, with a failure to induce protection against paralytic poliomyelitis in certain population segments in some parts of the world.
Pearay L, Ogra, Hiromasa, Okayasu, Cecil, Czerkinsky, Roland W, Sutter   +3 more
openaire   +2 more sources