Results 31 to 40 of about 244,373 (296)

Monoclonal antibody against EV71 3Dpol inhibits the polymerase activity of RdRp and virus replication

BMC Immunology, 2019
Background Enterovirus A 71 (EV71) is a neurotropic virus that may lead to acute flaccid paralysis, encephalitis, cardiopulmonary failure or even death. No vaccine and defensive drug controlling EV71 is currently available, novel and efficient antiviral ...
Yaoming Li, Jie Yu, Xiuwen Qi, Huimin Yan   +3 more
doaj   +1 more source

TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica. [PDF]

, 2013
Our gastrointestinal tract is a portal of entry for a number of bacteria and viruses. Thus, this tissue must develop ways to induce antigen-specific T cell and antibody responses quickly.
DePaolo, R William, Kamdar, K, Karpus, WJ, Khakpour, S, Sugiura, Y, Young, G   +5 more
core   +1 more source

Effects of date palm fruit extracts on skin mucosal immunity, immune related genes expression and growth performance of common carp (Cyprinus carpio) fry [PDF]

, 2015
The aim of this study was to investigate the effects of date palm fruit extracts (DPFE) on skin mucosal immunity, immune related genes expression and growth performance of fry common carp (Cyprinus carpio). One hundred and twenty specimens (4.06 ± 0.13 g)
Attar, M., Cordero, H., Esteban, M.A., Hoseinifar, S.H., Khalili, M., Raeisi, M., Rufchaei, R.   +6 more
core   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Else KJ, Garcia FT, McSharry C, Nakajima H, Oku Y, Pawlowski Z, Petit‐Frere C, Robinson K, Tilney LG, Urban JF, WHO, WHO   +11 more
core   +4 more sources

Alveolar Macrophages: Adaptation to Their Anatomic Niche during and after Inflammation

Cells, 2021
At the early stages of life development, alveoli are colonized by embryonic macrophages, which become resident alveolar macrophages (ResAM) and self-sustain by local division.
Florian Pierre Martin, Cédric Jacqueline, Jeremie Poschmann, Antoine Roquilly   +3 more
doaj   +1 more source

Dendritic cell subsets in the intestinal lamina propria: ontogeny and function [PDF]

, 2013
The intestinal mucosa is exposed to large amounts of foreign antigen (Ag) derived from commensal bacteria, dietary Ags, and intestinal pathogens. Dendritic cells (DCs) are believed to be involved in the induction of tolerance to harmless Ags and in ...
Agace, Agace, Agace, Aliberti, Anjuere, Annacker, Bachem, Bachem, Bain, Banchereau, Bedoui, Bogunovic, Carter, Cebula, Cerovic, Chervonsky, Coombes, Crozat, Cruickshank, del Rio, del Rio, Denning, Diehl, Edelson, Edelson, Farache, Forster, Fujimoto, Ginhoux, Greter, Hadis, Halle, Hammerschmidt, Haniffa, Hildner, Hoshi, Ichikawa, Iwata, Jackson, Jaensson, Jaensson-Gyllenback, Jang, Johansson-Lindbom, Johansson-Lindbom, Jones, Jongbloed, Kinnebrew, Kobayashi, Kusunoki, Lewis, Liu, Macpherson, Maynard, McDole, Merad, Miller, Milling, Molenaar, Mucida, Naik, Naik, Niess, Onai, Persson, Poulin, Poulin, Rescigno, Rivollier, Sathaliyawala, Schlitzer, Schulz, Scott, Siddiqui, Sun, Svensson, Tamoutounour, Travis, Uematsu, Uematsu, Vallon-Eberhard, Varol, Vremec, Weiss, Worbs, Wu, Zeng, Zhan, Zigmond   +87 more
core   +1 more source

Mucosal immunity to poliovirus [PDF]

Mucosal Immunology, 2022
A cornerstone of the global initiative to eradicate polio is the widespread use of live and inactivated poliovirus vaccines in extensive public health campaigns designed to prevent the development of paralytic disease and interrupt transmission of the virus.
Connor, Ruth I, Brickley, Elizabeth B, Wieland-Alter, Wendy F, Ackerman, Margaret E, Weiner, Joshua A, Modlin, John F, Bandyopadhyay, Ananda S, Wright, Peter F   +7 more
openaire   +3 more sources

Nasal IgA Provides Protection against Human Influenza Challenge in Volunteers with Low Serum Influenza Antibody Titre

Frontiers in Microbiology, 2017
In spite of there being a number of vaccines, influenza remains a significant global cause of morbidity and mortality. Understanding more about natural and vaccine induced immune protection against influenza infection would help to develop better ...
Victoria M. W. Gould, James N. Francis, Katie J. Anderson, Bertrand Georges, Alethea V. Cope, John S. Tregoning   +5 more
doaj   +1 more source

Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function

Frontiers in Immunology, 2022
The studies described here provide an analysis of the pathogenesis of Blau syndrome and thereby the function of NOD2 as seen through the lens of its dysfunction resulting from Blau-associated NOD2 mutations in its nucleotide-binding domain (NBD). As such,
Liming Mao, Liming Mao, Atika Dhar, Guangxun Meng, Guangxun Meng, Guangxun Meng, Ivan Fuss, Kim Montgomery-Recht, Zhiqiong Yang, Qiuyun Xu, Atsushi Kitani, Warren Strober   +11 more
doaj   +1 more source

Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]

, 2019
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR, Elena Stylianou, Helen McShane, Matthew J. Paul, Rajko Reljic, Resende Co T, Rodriguez A, Uranga S, Wong EA   +8 more
core   +1 more source