Results 121 to 130 of about 2,570,818 (334)

Author Correction: Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity

Nature Communications, 2023
Chun Jing Wang, Lina Petersone, Natalie M. Edner, Frank Heuts, Vitalijs Ovcinnikovs, Elisavet Ntavli, Alexandros Kogimtzis, Astrid Fabri, Yassin Elfaki, Luke P. Houghton, Ralf J. Hosse, David A. Schubert, Andreas P. Frei, Ellen M. Ross, Lucy S. K. Walker   +14 more
doaj   +1 more source

Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis

Journal of Lipid Research
Patients with rheumatoid arthritis (RA) are at elevated risk of thrombotic events, yet the underlying mechanisms remain unknown. The contribution of the procoagulant membrane surface provided by aminophospholipids (aPLs) in driving thrombotic risk in RA ...
Daniela O. Costa, Majd B. Protty, Victoria J. Tyrrell, Ali A. Hajeyah, Bethan H. Morgan, Ben Mead, Martin Giera, Peter W. Collins, P. Vince Jenkins, Ernest Choy, Simon A. Jones, Valerie B. O’Donnell   +11 more
doaj   +1 more source

Some Aspects of Immunity in Virus Diseases [Abstract] [PDF]

, 1959
F. O. MacCallum
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Immunity in Rocky Mountain Spotted Fever [PDF]

, 1924
C. L. Connor
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Batch Correction and Comparison of Intracellular Signaling Among Multiple Rheumatic and Inflammatory Diseases

Journal of Probability and Statistics
Assays that measure intracellular signaling can provide an especially mechanistic assessment of cellular states and are thereby useful for uncovering cellular physiology.
Tyson H. Holmes, Michael Couse, Yael Rosenberg-Hasson, Rosemary Fernandez, Ajay Fernandez, Kavita Mathi, Joel M. Guthridge, Judith A. James, Julie M. Yabu, Francois Haddad, P. J. Utz, Antonio Hardan, C. Garrison Fathman, Mark M. Davis, Holden T. Maecker   +14 more
doaj   +1 more source

Biovail v. Hoechst Aktiengesellschaf, Inc: An Analysis Under the Sherman Act and the Noerr-Pennington Doctrine [PDF]

, 2017
The Hatch-Waxman Act of 1984 regulates approval by the Food and Drug Administration (“FDA”) of generic counterparts to patented drugs. In a series of recent cases, large pharmaceutical companies have been accused of exploiting Hatch-Waxman in violation ...
Resek, John F., Ph.D.
core   +1 more source

Inheritance of immunity to mildew in peruvian forms of Pisum sativum [PDF]

, 1948
S. C. Harland
openalex   +1 more source