Results 291 to 300 of about 2,570,818 (334)

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Immune Surveillance and Immune Escape in Cancer: Mechanisms and Immunotherapy. [PDF]

MedComm (2020)
Peng Y, Zhan L, Shi J, Wang J, Li Y, Sun X, Lv J, Yang H, Qiu Z, Liu X, Li C, Gong S, Jia W, Wang H, Zhao Y, Zhang B, Guo W, Guo J, Shang J, Zhou Q, Yang Y, Gao F.   +21 more
europepmc   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Measles Outbreaks and Implications for Patients Receiving Stem Cell or Cellular Therapies in Canada: Cell Therapy Transplant Canada (CTTC) Infectious Diseases Working Committee. [PDF]

Curr Oncol
Dufresne SF, Shahmirzadi MR, Deotare U, Kabbani D, Husain S, Rotstein C, Hosseini-Moghaddam SM.   +6 more
europepmc   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

RNA-binding proteins orchestrating immunity in plants. [PDF]

Plant J
Bach-Pages M, Menon A, Wadley B, Castello A, Preston GM.   +4 more
europepmc   +1 more source

Gut microbiota as a regulator of vaccine efficacy: implications for personalized vaccination. [PDF]

Gut Microbes
Lu Q, Feng Y, Wang H, Zhu K, Teng L, Yue M, Li Y.   +6 more
europepmc   +1 more source

The cGAS‒STING pathway in colorectal cancer: bridging innate immunity and therapeutic strategies. [PDF]

J Exp Clin Cancer Res
Li WJ, Dong GH, Bi Y, Han YY, Sun LL, Wang T, Lin ZH, Ren XS.   +7 more
europepmc   +1 more source

A Simple Deterministic Model of Protection and Cost Benefits from Vaccinating Indian Cattle Against Infectious Bovine Rhinotracheitis. [PDF]

Pathogens
Ganguly B, Tayshete S, Pattnaik P, Bhargav NSN, Kanakasapapathy AK.   +4 more
europepmc   +1 more source