Results 171 to 180 of about 121,206 (265)

The Myeloma Risk Variant of TNFRSF13B Shows Reduced NF‐κB Signalling Activity in HEK293 Cells

European Journal of Haematology, EarlyView.
ABSTRACT A single nucleotide variant rs34562254 in TNFRSF13B, which encodes TACI (transmembrane activator and CAML interactor), is associated with an increased risk of myeloma and MGUS. This variant encodes a proline to leucine substitution at residue 251 in the long isoform (P251L) and residue 205 in the short isoform (P205L) of TACI.
Richard Muyan Chen, Jackie L. Ludgate, Robert J. Weeks, Heather E. Cunliffe, Ali G. Dohan, Ian M. Morison   +5 more
wiley   +1 more source

Immunogenic insights and experimental validation of a multiepitope vaccine construct against <i>Streptococcus pneumoniae</i>. [PDF]

Front Immunol
Devarakonda Y, Reddy MVNJ, Binu A, Syal K.   +3 more
europepmc   +1 more source

Simultaneous modification of Thermotoga maritima encapsulin subunits to produce multivalent nanoparticle vaccines for non‐typhoidal Salmonella enterica

The FEBS Journal, EarlyView.
This study investigates the modularity of encapsulin—a protein nanoparticle—by simultaneously inserting up to four distinct Salmonella epitopes within the encapsulin subunit. The encapsulin variants were transiently expressed in plants where they assembled into nanoparticles; however, their accumulation and stability varied depending on the ...
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

Antibody-mediated diversification of primary and secondary humoral immune responses. [PDF]

J Exp Med
Schaefer-Babajew D, Binet L, Silva Santos GS, Ruprecht C, Deimel LP, ElTanbouly MA, Gharrassi D, Lima Dos Reis G, Uhe C, Yao KH, Hernandez B, Agrawal P, Gazumyan A, Stamatatos L, Hartweger H, Nussenzweig MC.   +15 more
europepmc   +1 more source

Coloniality of Skill Codification: A Decolonial Feminist Analysis of “Ideal Workers” in the “Future of Work” Policy Discourses

Gender, Work &Organization, EarlyView.
ABSTRACT Over the last decade, policy actors have produced a surge of “future of work” reports that reimagine workers through the dual logics of digitalization and human capital. Drawing on 25 policy documents (WEF, World Bank, OECD, EU, and major consultancies) and combining Bacchi and Goodwin's WPR approach with decolonial feminist theory, this paper
Muneeb Ul Lateef Banday
wiley   +1 more source

Strengthening the Immunization System Through Private Provider Engagement to Improve Vaccine Uptake in Urban Settlements of Karachi, Pakistan: A Before-After Study. [PDF]

Vaccines (Basel)
Memon Z, Ali A, Habib S, Ahmed W, Ansar F, Kalwar M, Azam I, Aftab L, Bhurgri A, Zaidi S.   +9 more
europepmc   +1 more source

Potential association of cluster headache with certain COVID‐19 vaccines: An assessment from the pharmacovigilance databases

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background The main objective of our study was to assess the potential association between coronavirus disease 2019 (COVID‐19) vaccination and cluster headache (CH) using a pharmacovigilance approach. A secondary objective was to determine whether COVID‐19 vaccines predominantly triggered onset or worsening of the disease.
Elise K. Van Obberghen, Laura Parigny, Nouha Ben‐Othman, Elliot Ewig, Milou‐Daniel Drici, Alexandre O. Gérard, Sophie Gautier, Michel Lanteri‐Minet   +7 more
wiley   +1 more source

Geographic and Temporal Variations in Immunization Coverage in Nepal: An Ecological Time-Trend Analysis. [PDF]

Health Sci Rep
Rana K, Pandey SR, Chimoriya R, Poudel P, Shrestha BMS, Okheda SK, Chimoriya R.   +6 more
europepmc   +1 more source

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

Hepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura, Shinji Shimoda, Ryoka Masuda, Tram Nguyen Thi, Rui Yang, Quynh Nguyen Thi, Dong Le Thanh, Yuko Tamano, Yasunori Sato, Taro Yamashita, Kenichi Harada   +10 more
wiley   +1 more source

Geospatial Settlement Data and Immunization Reach in Polio SIAs: Evidence from Axis of Intractable Transmission States in Northern Nigeria. [PDF]

Gates Open Res
Shehu A, Metiboba L, Ohiaeri N, Ilesanmi O, Akpan D, Fashoto B, Nwakaogor GU, Fawaz A, Akhigbe O, Odukoya A, Akindipe O, Daniel F.   +11 more
europepmc   +1 more source