Results 181 to 190 of about 4,097 (210)

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Unveiling Disparities and Missed Opportunities in Vitamin A Supplementation Among Children Under Five in Ethiopia

Maternal &Child Nutrition, EarlyView.
Vitamin A supplementation (VAS) coverage in Ethiopia remains low (21%), with substantial inequities favoring wealthier, urban, and agrarian households, and missed opportunities to integrate VAS with health services like measles vaccination. Improving coverage, equity, and resilience requires expanding access, tailoring delivery approaches, and ...
Tsedey Moges, Meron Girma, Alemnesh Petros, Nardos Birru, Alemayehu Hussen, Meseret Woldeyohannes, Abiy Tefera, Tadesse Kebebe, Berhanu Wodajo, Getachew Tollera, Mesay Hailu, Stanley Chitekwe, Hiwot Darsene, Kidist Woldesenbet, Kaleab Baye, Masresha Tessema, Ramadhani Noor   +16 more
wiley   +1 more source

Rethinking Growth Monitoring and Promotion in the Era of Universal Health Coverage: Qualitative Assessment of Programme Delivery Challenges in Ethiopia

Maternal &Child Nutrition, EarlyView.
ABSTRACT Growth monitoring and promotion (GMP) programmes have been implemented for decades in almost all countries. Despite this long history of implementation, GMP has been criticised for being ineffective, calling for a rethink of the programme. With a view of contributing evidence towards the redesign of GMP, we conducted a qualitative evaluation ...
Bereket Gebremichael, Kaleab Baye, Yetayesh Maru, Ramadhani Noor, Firehiwot Mengistu, Hiwot Darsene, Yilkal Simachew, Tegene L. Dadi, Rahel Dereje, Stanley Chitekwe   +9 more
wiley   +1 more source

Diet and Care Mediate the Effects of Parenting and Nutrition Interventions on Childhood Infections

Maternal &Child Nutrition, EarlyView.
ABSTRACT The effect of community‐based multi‐input interventions that promote health, nutrition, and development on childhood infections, and the pathways that explain these effects remain unclear. We conducted a secondary analysis of a factorial‐designed clustered randomized controlled trial (N = 1489) conducted in rural Pakistan to estimate the ...
Nazia Binte Ali, Arjumand Rizvi, Saima Siyal, Wafaie W. Fawzi, Aisha K. Yousafzai, Christopher R. Sudfeld   +5 more
wiley   +1 more source

Indoor residual spraying of distinct insecticide formulations in a household‐scale micro‐mosaic format: Feasibility and effectiveness for malaria vector control in rural Zambia

Medical and Veterinary Entomology, EarlyView.
Densities of all Anopheles species were approximately comparable across all IRS regimes. No differences observed between treatment regimes regarding species composition of the Anopheles funestus group or An. gambiae complex. This operational pilot demonstrates the practical feasibility of IRS micro‐mosaics, despite the inherent increase in deployment ...
Dingani Chinula, Kenzo Mumba, Reuben Zulu, Ketty Ndhlovu, Deogratius R. Kavishe, Neil Philip Hobbs, Samson Kiware, Thomas Reed, Busiku Hamainza, Gerry F. Killeen   +9 more
wiley   +1 more source

Therapy With Doxycycline and Hydroxychloroquine Enables Surgical Excision of Ulcerated Cutaneous Granulomas in a Patient With Ataxia Telangiectasia

Pediatric Dermatology, EarlyView.
ABSTRACT The rubella virus vaccine strain can cause granulomas in patients with inborn errors of immunity that may evolve into chronic, recalcitrant ulcers. This report details treatment of ulcerated rubella granulomas in a patient with ataxia telangiectasia with doxycycline and hydroxychloroquine resulting in partial ulcer healing within 4 weeks ...
Luis Murguía‐Favela, Sofia Maruschak‐Love, Robertson A. Harrop, Marie‐Anne Brundler, Kyle Kurek, Kevin Fonseca, Michele L. Ramien   +6 more
wiley   +1 more source

The role of acquired host immunity in periodontal diseases

Periodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane, David F. Lappin, Shauna Culshaw   +2 more
wiley   +1 more source

Trust Norms, Distrust, and Worst‐Case Defiance in the COVID‐19 Pandemic

Regulation &Governance, EarlyView.
ABSTRACT When pandemics threaten, governments are expected to protect citizens. Trustworthiness and trust are central to meeting public expectations. Motivational posturing theory differentiates resistant and dismissive defiance during the COVID‐19 pandemic.
Valerie Braithwaite
wiley   +1 more source

National Health Insurance Reform in Indonesia: Health Care Usage and Expenditure Patterns When Expanding Population Coverage

Review of Development Economics, EarlyView.
ABSTRACT In 2014, Indonesia took a large step toward Universal Health Coverage and protection from the economic risk of illness—previous health insurance schemes were joined aiming to cover the entire population. This reform made it the largest single‐payer public health insurance scheme worldwide, which covered approximately 77% of Indonesian ...
Lisa Rogge
wiley   +1 more source