Results 41 to 50 of about 653,583 (338)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Epidemic processes with immunization

, 2003
We study a model of directed percolation (DP) with immunization, i.e. with different probabilities for the first infection and subsequent infections. The immunization effect leads to an additional non-Markovian term in the corresponding field theoretical
A.S. Perelson, Andrea Jiménez-Dalmaroni, C. Lopez, D. Mollison, F. Schlögl, F. van Wijland, H. Hinrichsen, H. Hinrichsen, H. Hinrichsen, H. Hinrichsen, H.K. Janssen, H.K. Janssen, Haye Hinrichsen, I. Jensen, I. Jensen, I. Jensen, J.-P. Bouchaud, J.F.F. Mendes, J.L. Cardy, J.L. Cardy, J.L. Cardy, K. Oerding, L.H. Tang, M.A. Muñoz, M.A. Muñoz, M.A. Muñoz, P. Fröjdh, P. Grassberger, P. Grassberger, P. Grassberger, P. Grassberger, P. Grassberger, P. Rupp, P.K. Mohanty, R. Dickman, R. Dickman, R.M. Ziff, S.N. Majumdar, S.V. Buldyrev, W. Hwang, Z. Alexandrowicz   +40 more
core   +1 more source

Value and effectiveness of National Immunization Technical Advisory Groups in low- and middle-income countries : A qualitative study of global and national perspectives [PDF]

, 2019
© The Author(s) 2019. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.The Global Vaccine Action Plan proposes that every country establish or have access to a National Immunization Technical ...
Bell, Sadie, Blanchard, Laurence, Howard, Natasha, Mounier-Jack, Sandra, Walls, Helen   +4 more
core   +3 more sources

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Immunization for complex network based on the effective degree of vertex

, 2011
The basic idea of many effective immunization strategies is first to rank the importance of vertices according to the degrees of vertices and then remove the vertices from highest importance to lowest until the network becomes disconnected.
Barabási A.-L., Boguñá M., Diekmann O., Hu K., KE HU, Li Y., Milo R., Moreno Y., Yan G., YI TANG, Zhou T.   +10 more
core   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Post-marketing safety surveillance study of a 9-valent human papillomavirus vaccine in individuals aged 16–26 years in Chongqing, China

Human Vaccines & Immunotherapeutics, 2023
The safety of human papillomavirus (HPV) vaccines, one of the major challenges to public vaccination, has been controversial. This study assessed the adverse reactions of 9-valent HPV (9vHPV) vaccines.
Yuan-yuan Zhang, Jia-Wei Xu, Yang Liu, Wei Qiu, Pei-Ning Bai, Yi Zeng, Qing Wang   +6 more
doaj   +1 more source

Molecular signatures of a TLR4 agonist-adjuvanted HIV-1 vaccine candidate in humans [PDF]

, 2018
Systems biology approaches have recently provided new insights into the mechanisms of action of human vaccines and adjuvants. Here, we investigated early transcriptional signatures induced in whole blood of healthy subjects following vaccination with a ...
Anderson, J, Harandi, AM, Kratochvil, S, McKay, PF, Olafsdottir, TA, Persson, J, Shattock, RJ, östensson, M   +7 more
core   +2 more sources

Dynamic SARS-CoV-2-specific B-cell and T-cell responses following immunization with an inactivated COVID-19 vaccine [PDF]

, 2021
Yuxin Chen, Shengxia Yin, Xin Tong, Yue Tao, Jun Ni, Jie Pan, Ming Li, Yawen Wan, Minxin Mao, Yali Xiong, Xiaomin Yan, Yue Yang, Rui Huang, Chao Wu, Han Shen   +14 more
openalex   +1 more source

Immune Logics ain't that Immune

Logic and Logical Philosophy, 2022
Da Ré and Szmuc argue that while there is a symmetry between ‘infectious’ and ‘immune’ logics, this symmetry fails w.r.t. extending an algebra with an immune or an infectious element. In this paper, I show that the symmetry also fails w.r.t. defining a new logical operation from a given set of primitive (Boolean) operations.
openaire   +2 more sources