Results 51 to 60 of about 658,898 (341)

Immunization for complex network based on the effective degree of vertex

open access: yes, 2011
The basic idea of many effective immunization strategies is first to rank the importance of vertices according to the degrees of vertices and then remove the vertices from highest importance to lowest until the network becomes disconnected.
Barabási A.-L.   +10 more
core   +1 more source

Skin Immunity [PDF]

open access: yesArchivum Immunologiae et Therapiae Experimentalis, 2017
Skin is the largest organ of the body with a complex network of multitude of cell types that perform plastic and dynamic cellular communication to maintain several vital processes such as inflammation, immune response including induction of tolerance and disease prevention, wound healing, and angiogenesis.
openaire   +3 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

open access: yesAdvanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales   +11 more
wiley   +1 more source

Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]

open access: yes, 2015
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam   +3 more
core   +3 more sources

Heteroclitic Immunization Induces Tumor Immunity [PDF]

open access: yesThe Journal of Experimental Medicine, 1998
In tumor transplantation models in mice, cytotoxic T lymphocytes (CTLs) are typically the primary effector cells. CTLs recognize major histocompatibility complex (MHC) class I–associated peptides expressed by tumors, leading to tumor rejection. Peptides presented by cancer cells can originate from viral proteins, normal self-proteins regulated during ...
R, Dyall   +9 more
openaire   +2 more sources

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Research Trends of Vaccination-Related Systematic Reviews, 2011–2023: A Bibliometric Analysis

open access: yesPublications
Systematic reviews (SRs) reflect the best available evidence for informing vaccination recommendations. This study presents a bibliometric analysis of vaccination-related SRs aiming to uncover research trends.
Antonia Pilic   +8 more
doaj   +1 more source

Reducing missed opportunities for vaccination in selected provinces of Mozambique: A study protocol [version 1; referees: 2 approved]

open access: yesGates Open Research, 2017
Background: A missed opportunity for vaccination (MOV) refers to any contact with health services by an individual who is eligible for vaccination, which does not result in the person receiving the vaccine doses for which he or she is eligible.
Bvudzai Priscilla Magadzire   +3 more
doaj   +1 more source

Value and effectiveness of National Immunization Technical Advisory Groups in low- and middle-income countries : A qualitative study of global and national perspectives [PDF]

open access: yes, 2019
© The Author(s) 2019. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.The Global Vaccine Action Plan proposes that every country establish or have access to a National Immunization Technical ...
Bell, Sadie   +4 more
core   +3 more sources

Unfolding and Degradation of Micellar Immunodrug Carriers Derived From End Group Modified Aliphatic Poly(Carbonate)s with Acid‐Responsive Ketal Side Groups

open access: yesAdvanced Materials, EarlyView.
An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck   +16 more
wiley   +1 more source

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