Results 51 to 60 of about 653,583 (338)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Unfolding and Degradation of Micellar Immunodrug Carriers Derived From End Group Modified Aliphatic Poly(Carbonate)s with Acid‐Responsive Ketal Side Groups

Advanced Materials, EarlyView.
An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck, Michael Fichter, Laura J. Rosenberger, Jannis Willig, Alexander Fuchs, Felicia Schön, Paul Schneider, Carolina Medina‐Montano, Taufiq Ahmad, Jessica Erlenbusch, Pol Besenius, Leonard Kaps, Matthias Bros, Stephan Grabbe, Volker Mailänder, Jürgen Groll, Lutz Nuhn   +16 more
wiley   +1 more source

Reducing missed opportunities for vaccination in selected provinces of Mozambique: A study protocol [version 1; referees: 2 approved]

Gates Open Research, 2017
Background: A missed opportunity for vaccination (MOV) refers to any contact with health services by an individual who is eligible for vaccination, which does not result in the person receiving the vaccine doses for which he or she is eligible.
Bvudzai Priscilla Magadzire, Gabriel Joao, Stephanie Shendale, Ikechukwu Udo Ogbuanu   +3 more
doaj   +1 more source

Reactive immunization on complex networks

, 2017
Epidemic spreading on complex networks depends on the topological structure as well as on the dynamical properties of the infection itself. Generally speaking, highly connected individuals play the role of hubs and are crucial to channel information ...
Alfinito, Eleonora, Beccaria, Matteo, Fachechi, Alberto, Macorini, Guido   +3 more
core   +1 more source

Containing epidemic outbreaks by message-passing techniques [PDF]

, 2013
The problem of targeted network immunization can be defined as the one of finding a subset of nodes in a network to immunize or vaccinate in order to minimize a tradeoff between the cost of vaccination and the final (stationary) expected infection under ...
Altarelli, F., Braunstein, A., Dall'Asta, L., Wakeling, J. R., Zecchina, R.   +4 more
core   +3 more sources

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Influenza and pertussis vaccination during pregnancy – attitudes, practices and barriers in gynaecological practices in Germany

BMC Health Services Research, 2019
Background In Germany, antenatal influenza vaccination is recommended since 2010, but uptake remains low. Several countries recently introduced antenatal pertussis vaccination, which is currently under consideration in Germany.
Stefanie Böhm, Marianne Röbl-Mathieu, Burkhard Scheele, Michael Wojcinski, Ole Wichmann, Wiebke Hellenbrand   +5 more
doaj   +1 more source

Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]

, 2019
Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano, De Zutter, Lieven, Garmyn, An, Haesebrouck, Freddy, Heyndrickx, Marc, Martel, An, Pasmans, Frank, Van Rysselberghe, Nathalie, Vandeputte, Jasmien   +8 more
core   +1 more source

Research Progress in Wearable Microneedle Sensors for Health Analysis

Advanced Sensor Research, EarlyView.
Wearable biosensors are transforming personal healthcare by enabling minimally invasive, molecular‐level monitoring. Emerging electrochemical microneedle sensors can detect analytes in interstitial fluid, enabling painless extraction and real‐time tracking.
Adnan Zameer, Yang Guo, Hongda Wang, Qiang Zhang   +3 more
wiley   +1 more source

Research Trends of Vaccination-Related Systematic Reviews, 2011–2023: A Bibliometric Analysis

Publications
Systematic reviews (SRs) reflect the best available evidence for informing vaccination recommendations. This study presents a bibliometric analysis of vaccination-related SRs aiming to uncover research trends.
Antonia Pilic, Louise Henaff, Christoph A. Steffen, Hanna Helene Linß, Antonia Isabelle Dreyer, Madeleine Batke, Ole Wichmann, Vanessa Piechotta, Thomas Harder   +8 more
doaj   +1 more source