Results 61 to 70 of about 2,173,693 (307)
Advanced Science, EarlyView.A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen +14 more
wiley +1 more source
Dentist in mission indradhanush: A target-to-target India's unvaccinated children
Dentistry and Medical Research, 2017 Introduction: Immunization is one of the most effective, safest, and efficient public health interventions and was first introduced in India in 1978. While the impact of immunization on childhood morbidity and mortality has been great, its full potential
Ravneet Malhi +5 more
doaj +1 more source
Advanced Science, EarlyView.Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang +6 more
wiley +1 more source
Immunization in developing countries : its political and organizational determinants [PDF]
The authors use cross-national social, political, economic, and institutional data to explain why some countries have stronger immunization programs than others, as measured by diphtheria-tetanus-pertussis (DTP) and measles vaccine coverage rates and the
Gauri, Varun, Khaleghian, Peyvand
core
Online Brazilian Journal of Nursing, 2006 The objective of this exploratory, transversal, and descriptive study was to identify the vaccination situation of Nursing students and their adhesion the Adult Immunization Program, defined by the Ministry of Health.
Ana Louisa de Araújo Carvalho +2 more
doaj
Estimating the cost of vaccination in southeastern Iran
Human Vaccines & Immunotherapeutics, 2020 Background: Specification of vaccination cost of children would help policymakers in determining the nation-wide budget needed for the maintenance of the vaccination program.
Reza Goudarzi +4 more
doaj +1 more source
Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3
Advanced Science, EarlyView.This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao +6 more
wiley +1 more source
Immunization strategies-2020 [PDF]
CDC is offering a series of weekly one-hour web-on-demand videos that will provide an overview of vaccination principles, general best practices, immunization strategies, and specific information about vaccine-preventable diseases and the vaccines that ...
core
Advanced Science, EarlyView.In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao +6 more
wiley +1 more source
Planning influenza vaccination programs: a cost benefit model
Cost Effectiveness and Resource Allocation, 2012 Background Although annual influenza vaccination could decrease the significant economic and humanistic burden of influenza in the United States, immunization rates are below recommended levels, and concerns remain whether immunization programs can be ...
Duncan Ian G +3 more
doaj +1 more source