Proficiency Testing of Viral Marker Screening in African Blood Centers - Seven African Countries, 2017. [PDF]
A 2014 report evaluating accuracy of serologic testing for transfusion-transmissible viruses at African blood center laboratories found sensitivities of 92%, 87%, and 90% for detecting infections with human immunodeficiency virus (HIV), hepatitis B virus
Benech, Irene +10 more
core
Healthcare workers in Saudi Arabia (KSA) perceive stress differently according to gender but not in cortisol levels - an immunoassay study [PDF]
Background: Working in the healthcare sector is generally regarded as stress inductive, which hampers performance, yet one demanding constant accuracy.
Alyusuf, Danah A +2 more
core +1 more source
Investigating factors associated with thyroid hormone measurements during pregnancy
Background: Accurate assessment of thyroid status is essential for maternal and fetal management during pregnancy. This study measured human chorionic gonadotropin (HCG), albumin, and thyroxine-binding globulin (TBG) levels during pregnancy to clarify ...
Miho Fukushita +13 more
doaj +1 more source
QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Development of a nucleic acid lateral flow immunoassay for simultaneous detection of Listeria spp. and Listeriamonocytogenes in food [PDF]
We present a new nucleic acid lateral flow immunoassay (NALFIA) for the assessment of listeria contamination. The detection procedure starts with enrichment of sample in Half Fraser broth (24 h). Following isolation of DNA, a duplex PCR is performed with
Amerongen, A., van +3 more
core +2 more sources
An Overview of Biotin Interference Impact on Immunoassays
The interference of high concentrations of biotin in patients’ serum with certain immunoassays can lead to inaccurately high or low test results, which may confuse physicians and contribute to misdi-agnosis and inappropriate treatment.
Alfatih Aboalbasher Yousif +11 more
doaj +1 more source
A Plug‐and‐Play Volume Minimizing Micromixer
ABSTRACT Microscale fluid mixing has numerous applications where rapid and efficient mixing is required, including drug discovery, bio‐analysis and point‐of‐care diagnostics. Conventional soft lithography processes, however, make the integration of robust and reliable mixing difficult to implement in practice, especially across different flow rates ...
Kirill Kolesnik +3 more
wiley +1 more source
Enzyme-linked immunosorbent assay for urinary albumin at low concentrations [PDF]
We describe an enzyme-linked immunosorbent assay (ELISA) for urinary albumin. It requires only commercially available reagents, can detect as little as 16 micrograms of albumin per liter, and analytical recovery ranges from 92 to 116%.
Jesse, U. +4 more
core
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He +10 more
wiley +1 more source

