Results 121 to 130 of about 203,057 (268)

Experimental methods in chemical engineering: Magnetometry

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Magnetometry is a non‐invasive technique to characterize the behaviour of magnetic materials of which the most common contain Fe, Co, and Ni. Vibrating sample magnetometers (VSMs) vibrate samples at a fixed frequency in a static, homogeneous magnetic field to induce a voltage in pick up coils according to Faraday's law of induction.
Michael Claeys   +3 more
wiley   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

Operationalizing Precision Medicine in Drug Development: Predictive Biomarkers, Companion Diagnostics, and Regulatory Pathways

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg   +1 more
wiley   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke   +12 more
wiley   +1 more source

A multivariable probability score integrating routine immunoassay results for the immunological assessment of antisynthetase syndrome. [PDF]

open access: yesFront Immunol
Luchoro JF   +8 more
europepmc   +1 more source

Localized 3D acoustic streaming in microdroplets using high‐frequency micro‐beam IDTs

open access: yesDroplet, EarlyView.
Miniaturized 160 MHz acoustic microbeam transducers, with a size much smaller than droplets, enable precise localized actuation, generating complex three‐dimensional streaming and tunable particle aggregation. This concept provides high‐resolution, non‐contact fluid manipulation for biosensing, lab‐on‐chip diagnostics, and targeted drug screening ...
D. Sánchez‐Saldaña   +2 more
wiley   +1 more source

An automated plasma-based proteotyping immunoassay for APOE ε4 zygosity classification in Alzheimer's disease. [PDF]

open access: yesAlzheimers Dement
Levin S   +15 more
europepmc   +1 more source

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