Results 221 to 230 of about 362,154 (309)

Comparative Analysis of Four Matrix Dilution Methods for Eliminating IgM Paraprotein Interference in Prealbumin and Uric Acid Assays: Based on Two Case Reports

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
IgM paraproteins can cause significant interference in prealbumin (PA) and uric acid (UA) measurements, leading to falsely abnormal results. We systematically compared four dilution methods to eliminate this interference. Dilution with the PA reagent (containing PEG) effectively restored accurate PA results.
Xiaowei Chi   +4 more
wiley   +1 more source

Validation of a Multiparametric, Automated, Macroarray‐Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The assay exploited a multiparametric and fully automated device applied to CHORUS EVO to validate that the CHORUS Macroarray Liver Diseases kit is a novel procedure for detecting autoantibodies of AIH and PBC. The assay resulted as linear, accurate, sensitive, specific, and able to distinguish between PBC and AIH.
Luigi Raganelli   +14 more
wiley   +1 more source

Evaluation of Soluble Triggering Receptor Expressed on Myeloid Cells 2 (sTREM2) in Cerebrospinal Fluid, Serum, and Plasma Using the Fully Automated Lumipulse Platform

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Relationship between serum and CSF sTREM2 concentration. ABSTRACT Background In this study, we first evaluated the relationship between sTREM2 concentrations in CSF, serum, and plasma of Alzheimer's disease (AD) patients using the newly developed Lumipulse G sTREM2 assay.
Luisa Agnello   +9 more
wiley   +1 more source

Clinical Interpretation of Platelet Activation Marker sCLEC‐2 in Antiphospholipid Syndrome

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Soluble C‐type lectin‐like receptor 2 (sCLEC‐2), a marker of platelet activation, was evaluated in patients with antiphospholipid syndrome (APS). Plasma sCLEC‐2 levels and the sCLEC‐2/D‐dimer ratio were significantly elevated in APS compared with other collagen diseases and healthy controls.
Risa Kaneshige   +3 more
wiley   +1 more source

Real‐World Utilization Patterns of Toxoplasmosis Diagnostic Testing in Korea: A Large‐Scale Laboratory‐Based Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We conducted a large retrospective analysis of real‐world Toxoplasma gondii IgG, IgM, and PCR testing performed at a nationwide referral laboratory in Korea to characterize diagnostic utilization patterns and test performance in routine clinical practice.
Rihwa Choi, Sang Gon Lee
wiley   +1 more source

Association Between Multi‐Laboratory Parameters Pre‐ and Post‐Treatment and Pathological Features and Their Values in Clinical Decision in Primary Hepatic Carcinoma

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Primary hepatic cancer (PHC), especially hepatocellular carcinoma (HCC), is still a significant burden worldwide. The efficacy of diagnosis, treatment response monitoring, and prognostication using laboratory biomarkers is still a challenge. This study analyzed multi‐laboratory parameters pre‐ and post‐treatment and their associations with clinical and
Xiaowei Chi   +3 more
wiley   +1 more source

Analytical Performance of Nanobody-Based Immunoassay and Immunosensing Platforms for Bacteria and Toxin Detection: A Systematic Review. [PDF]

open access: yesAntibodies (Basel)
Jalil A   +9 more
europepmc   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

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