Characterization of mouse switch variant antibodies by matrix-assisted laser desorption ionization mass spectrometry and electrospray ionization mass spectrometry [PDF]
, 1901 The amino acid sequences of mouse monoclonal antibodies have been characterized completely by mass spectrometry. Antibodies used in the present study were derived from mouse switch variant cell lines that produce four kinds of immunoglobulin Gs (IgGs ...
Akashi, Satoko +9 more
core +1 more source
Special immunobiologicals’ schedule applied to infants at a reference service in Ceará [PDF]
Revista Brasileira em Promoção da Saúde, 2010 Objective: To analyze the vaccine schedule for preterm infants in a program of special immunobiologicals. Methods: A documental study conducted at a Reference Center of Special Immunobiologicals (CREATE) situated in a general hospital of tertiary care in
Joselany Áfio Caetano +2 more
doaj
Immunobiology of xenotransplantation [PDF]
Transplant International, 2000 The transplantation of organs between disparate species is hindered by severe immune responses of the recipient against the graft. These immune responses gives rise to hyperacute and acute vascular rejection and to cellular rejection. Research during the past decade has shed light on the elements of the immune system responsible for the rejection of ...
openaire +2 more sources
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus. [PDF]
, 1990 We quantitated and characterized the changes in the human B cell repertoire, at the clonal level, before and after immunization with rabies virus. Moreover, we generated 10 monoclonal cell lines producing IgM, IgG, and IgA antibodies to the virus.
Casali, P +6 more
core
Immune system: part III. The delicate balance of the immune system between tolerance and autoimmunity [PDF]
, 2010 The immune system consists of an intricate network of organs, cells, and molecules responsible for maintaining the body's homeostasis and responding to aggression in general.
Andrade, Luiz Eduardo Coelho +6 more
core +3 more sources
Cancer Science, EarlyView.CD8+ T cell infiltration demonstrates distinct clinical significance across molecular subtypes of gastric cancer. High infiltration correlates with improved survival in EBV‐positive and CIN subtypes, while low infiltration predicts better adjuvant chemotherapy response in MSI patients.
Zhen Ling +9 more
wiley +1 more source
DNAMicrobial contamination is a critical challenge for the pharmaceutical industry, especially in thermosensitive sterile products, and can compromise their quality and safety.
Juliana Nunes Ramos +3 more
doaj +1 more source
Evaluation of Immunization Policies for PeaceKeeping Missions [PDF]
, 2017 This article first examines data bases available to assess the risk of vaccine-preventable diseases (VPD). In the second part, immunization recommendations and practices are briefly evaluated in view of the risk of exposure to VPD and of the efficacy and
Desaules, Madeleine +3 more
core
Adverse events following yellow fever vaccination in immunocompromised persons [PDF]
, 2021 This observational retrospective study conducted during an yellow fever (YF) outbreak in Sao Paulo, Brazil, in 2017-2018, describes adverse events (AE) following YF vaccination of immunocompromised persons.
Ibrahim, Karim Yaqub +4 more
core +2 more sources