Results 41 to 50 of about 1,013 (170)

PLA2R‐Positive Membranous Nephropathy and AA Amyloidosis in an Ethiopian Patient With Chronic Hepatitis B: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham, Leja Hamza, Azeb Kebede, Daniel Rebuma Bekele, Zekarias Amdemariam   +4 more
wiley   +1 more source

CD8+ T Cell Infiltration Elicits Molecular Subtype‐Biased Clinical Outcomes in Gastric Cancer Patients

Cancer Science, Volume 117, Issue 5, Page 1434-1445, May 2026.
CD8+ T cell infiltration demonstrates distinct clinical significance across molecular subtypes of gastric cancer. High infiltration correlates with improved survival in EBV‐positive and CIN subtypes, while low infiltration predicts better adjuvant chemotherapy response in MSI patients.
Zhen Ling, Jieti Wang, Yun Gu, Ziqiu Zhang, Fei Shao, Chao Lin, Hongyong He, Ruochen Li, Hao Liu, Jiejie Xu   +9 more
wiley   +1 more source

Histoplasma Urinary Antigen for the Diagnosis of Histoplasmosis in Non‐HIV Individuals

Mycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Histoplasmosis is an endemic mycosis in the Americas. While urinary Histoplasma antigen enzyme immunoassay testing (HAET) has been validated mainly in HIV‐infected patients with disseminated disease, its performance in HIV‐negative populations with heterogeneous clinical presentations is unclear.
João Nobrega de Almeida Jr, Tamara Harb Roca, Denise dos Anjos Laurentis de Souza Campos, Renée Zon Filippi, Cristóvão Luis P. Mangueira, Marines Dalla Valle Martino   +5 more
wiley   +1 more source

Telemedicine in the National Immunization Program (Brazil): A promising tool

Vaccine: X, 2022
The coronavirus disease 2019 pandemic abruptly changed the dynamics of basic health care, with the consequent need for adjustments in essential services. The objective of this study was to evaluate the acceptance and impact of telemedicine at a Reference
Luciana Gomes Pedro Brandão, Marcellus Dias da Costa, Pedro Silva Martins, Sergio Carlos Assis de Jesus-Junior, Daniele Fernandes de Aguiar, Alberto Santos de Lemos, Diogo Vicente Bittencourt Sacramento Dias, Charbell Miguel Haddad Kury, Lauro Amaral de Oliveira, Valter Montes de Almeida, Flavio de Carvalho, Ananza Tainá da Silva Santos, José Cerbino-Neto, Margareth Catoia Varela   +13 more
doaj   +1 more source

Vaccination Coverage and Factors Associated With Incomplete Vaccination Schedules in Children Under 5 in a Peripheral Area of the Federal District of Brazil

Public Health Nursing, Volume 43, Issue 3, Page 543-553, May/June 2026.
ABSTRACT Objective To estimate vaccination coverage (VC) and analyze the factors associated with the incomplete vaccination schedule (IVS) in children under 5 years of age in two Basic Health Units in the Federal District of Brazil. Design A cross‐sectional study.
Ivea Rayane Mendes Nicacio Viana, Henry Maia Peixoto   +1 more
wiley   +1 more source

REGISTRATION OF DATA ON THE USE OF IMMUNOBIOLOGICALS AND SUPPLIES IN VACCINE ROOMS

Cogitare Enfermagem, 2018
Objective: To verify the registration of the data on the use of immunobiologicals and supplies in the vaccination rooms of the public network. Method: a cross-sectional study, carried out in eight primary care vaccination rooms, with 106 observations
Taís Trombetta Dalla Nora, Giulliana Weigert Herrera, Graciele Fernanda da Costa Linch, Adriana Aparecida Paz   +3 more
doaj   +1 more source

Causal Exposures of Immune Cells in Neuromyelitis Optica Spectrum Disorders: A Mendelian Randomization Study and Flow Cytometry Analysis

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study used two‐sample Mendelian randomization to assess causal relationship of immune cells with NMOSD. We then enrolled 27 NMOSD patients and 17 healthy controls for peripheral blood flow cytometric analyses to validate part of MR findings. ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) are an immune‐mediated inflammatory ...
Jingru Ren, Jianchun Wang, Zhenyu Niu, Jing Guo, Nan Zhang, Hongjun Hao, Feng Gao, Ran Liu, Zhaoxia Wang   +8 more
wiley   +1 more source

Harnessing Tumor Organoids to Revolutionize Immunotherapy Research

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Immunotherapy has emerged as a revolutionary approach to cancer treatment, yet the lack of robust preclinical testing platforms impedes progress in this field. Tumor organoids, three‐dimensional structures derived from patient‐specific samples, differ from conventional models by faithfully recapitulating the histological, genetic, and ...
Zhen Wang, Peipei Yin, Shizhan Cui, Hui Liu, Dan Li, Yang Yu, Baoshan Cao, Xiaojuan Liu   +7 more
wiley   +1 more source

Longitudinal Monitoring of GRIm and HCC‐GRIm Scores Reveals Immunologically Relevant Prognostic Indicators in Hepatocellular Carcinoma Undergoing TACE Plus ICIs and Anti‐VEGF Antibodies/TKIs

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Objective To investigate the clinical significance and peripheral immunological basis underlying the dynamic changes of Gustave Roussy Immune (GRIm) score and the hepatocellular carcinoma‐specific GRIm (HCC‐GRIm) score in unresectable hepatocellular carcinoma (uHCC) patients treated with transarterial chemoembolization (TACE) combined with ...
Lihao Qin, Linzhou Zhu, Yu Wang, Wanci Li, Shuai Zhang, Jian Shen, Xiaoli Zhu   +6 more
wiley   +1 more source

The landscape of responses to neoadjuvant immunotherapy in resectable Kirsten rat sarcoma viral oncogene homolog‐mutant lung adenocarcinoma: Clinical heterogeneity and correlative immunologic analysis

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
KRAS‐mutant LUAD patients exhibit inferior pathological responses and survival after neoadjuvant immunotherapy compared to KRAS‐wildtype patients. A CD4T_Treg_TNFRSF4 subset is enriched in non‐responders, defining an immunosuppressive microenvironment. Responders are characterized by a synergistic network between Th1 cells and a novel exhausted‐like B ...
Sikai Wu, Jiheng Niu, Xiaowei Chen, Jinfei Li, Quanying Tang, Zhenlin Yang, Shugeng Gao   +6 more
wiley   +1 more source