Results 71 to 80 of about 2,086 (203)

Bacillus lumedeiriae sp. nov., a Gram-Positive, Spore-Forming Rod Isolated from a Pharmaceutical Facility Production Environment and Added to the MALDI Biotyper® Database

open access: yesMicroorganisms
A Gram-positive, aerobic, rod-shaped and spore-forming bacterium strain designation, B190/17, was isolated from an air monitoring sample of a Brazilian immunobiological production facility in 2017.
Luciana Veloso da Costa   +9 more
doaj   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma   +5 more
wiley   +1 more source

IMMUNOBIOLOGICALS [PDF]

open access: yes, 2018
Immunobiologicals are the biologically active agents with immunological actions that are useful for the management  of immunologically mediated diseases of infectious or non-infectious origin.Keywords :Immunobiologicals,Epitope,Interferon,Monoclonal ...
N, MOHAN, R, Karthik
core   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

open access: yesAdvanced Science, Volume 12, Issue 47, December 18, 2025.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai   +6 more
wiley   +1 more source

The Edna McConnell Clark Foundation's Tropical Disease Research Program: A 25-Year Retrospective Review 1976-1999 [PDF]

open access: yes, 2000
Documents and details the foundation's commitment to the program from its inception, and provides an analysis of its successes until the completion of the program in ...
Barnett L. Cline   +2 more
core  

Dual‐Function Plant‐Derived Nanovesicles From Regenerated Cannabis sativa Roots for Immunotherapy and Vaccine Delivery

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
Schematic diagram illustrating the immunotherapeutic and vaccine delivery potential of I‐PDNVs. ABSTRACT Cannabis sativa is a medicinal plant that produces a diverse array of pharmacologically active metabolites, making it a valuable resource for pharmaceutical applications. In this study, an adventitious root (AR) culture system was established from C.
Su Hyun Park   +11 more
wiley   +1 more source

Tumor Immune Contexture Model Predicts Prognosis and Immunotherapy Response in Gastric Cancer

open access: yesThe Journal of Gene Medicine, Volume 27, Issue 12, December 2025.
We developed the Tumor Immune Environment Score (TIES), an immune–stromal model derived from 1487 gastric cancers across seven cohorts. TIES integrates four axes—cancer–stroma remodeling, NK‐cell activity, TGF‐β signaling, and Th2 polarization—to stratify patients into high‐ and low‐risk groups. Low TIES tumors show immune‐inflamed features, higher TMB
Jiexuan Wang   +4 more
wiley   +1 more source

The use of biosimilar medicines in oncology - position statement of the Brazilian Society of Clinical Oncology (SBOC)

open access: yesBrazilian Journal of Medical and Biological Research, 2018
A biosimilar is a biologic product that is similar to a reference biopharmaceutical product, the manufacturing process of which hinders the ability to identically replicate the structure of the original product, and therefore, it cannot be described as ...
G.S. Fernandes   +6 more
doaj   +1 more source

B-Amyloid of Alzheimer\u27s Disease Induces Reactive Gliosis that Inhibits Axonal Outgrowth [PDF]

open access: yes, 1993
Pathological lesions in the brains of patients with Alzheimer\u27s disease (AD) are characterized by dense deposits of the protein ,B-amyloid. The link between the deposition of B-amyloid in senile plaques and AD-associated pathology is, at present ...
Canning, David R.   +6 more
core  

Programa Nacional de Imunização: Sistema Informatizado como opção a novos desafios [PDF]

open access: yes, 2015
The scope and coverage of the Brazilian Immunization Program can be compared with those in developed countries because it provides a large number of vaccines and has a considerable coverage.
Sato, Ana Paula Sayuri
core   +3 more sources

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