Results 181 to 190 of about 352,107 (336)

Label-free quantitative proteomics and immunoblotting identifies immunoreactive and other excretory-secretory (E/S) proteins of Anoplocephala perfoliata

open access: gold, 2022
Katja Hautala   +7 more
openalex   +1 more source

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

open access: yesAdvanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra   +23 more
wiley   +1 more source

The segmented flavivirus ALSV-encoded nucleoprotein VP2 inhibits type I interferon production by targeting RIG-I. [PDF]

open access: yesMicrobiol Spectr
Pan M   +13 more
europepmc   +1 more source

Genome-wide chromatin and gene expression profiling during memory formation and maintenance in adult mice. [Data Record 3: immunoblotting]

open access: green, 2016
Tonatiuh Peña Centeno   +7 more
openalex   +1 more source

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu   +7 more
wiley   +1 more source

APP ubiquitination by VHL protein is essential for MVB sorting and lysosomal degradation. [PDF]

open access: yesJ Mol Cell Biol
Shan C   +10 more
europepmc   +1 more source

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