Results 191 to 200 of about 352,107 (336)

SDS-PAGE and immunoblotting to assess whole-cell lysates from cell culture systems v1 [PDF]

open access: gold
Frances V Hundley   +3 more
openalex   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

open access: yesAdvanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang   +8 more
wiley   +1 more source

Deubiquitinase UCH-L1 confers paclitaxel resistance via stabilizing PKM2 to promote glycolysis in triple-negative breast cancer. [PDF]

open access: yesCell Death Dis
Chen X   +9 more
europepmc   +1 more source

Identification of antigenic components of Toxoplasma gondii by an immunoblotting technique [PDF]

open access: bronze, 1983
Paul Partanen   +5 more
openalex   +1 more source

UBE2T‐Driven p53 Degradation Rewires Glycolysis to Orchestrate Lactylation‐Mediated CAFs Activation and ECM Deposition in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study integrates multi‐omics to reveal the critical role of UBE2T in driving malignancy and stromal co‐evolution in PDAC. UBE2T potentiates glycolysis by regulating p53 degradation via a positive feedback loop, thereby promoting histone H3 lysine 18 lactylation in CAFs and stromal deposition. The UBE2T inhibitor PGG represents a potential strategy
Yong Ma   +16 more
wiley   +1 more source

Protective role of fatty acid oxidation against epithelial barrier dysfunction in allergic asthma. [PDF]

open access: yesRedox Rep
Wang M   +11 more
europepmc   +1 more source

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

open access: yesMolecular and Cellular Biology, 1985
G. Evan, G. Lewis, G. Ramsay, J. Bishop
semanticscholar   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

open access: yesAdvanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos   +12 more
wiley   +1 more source

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