Results 91 to 100 of about 224,518 (341)

Magnetic resonance imaging findings in central nervous system cryptococcosis: comparison between immunocompetent and immunocompromised patients

open access: yesRadiologia Brasileira, 2017
Objective To assess the magnetic resonance imaging (MRI) patterns associated with central nervous system infection with Cryptococcus sp. in relation to patient immune status.
Stênio Bruno Leal Duarte   +5 more
semanticscholar   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

open access: yesAdvanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi   +16 more
wiley   +1 more source

Perinephric abscess caused by fusarium chlamydosporum in an immunocompetent child: Case report and identification of the morphologically atypical fungal strain

open access: yesIndian Journal of Pathology and Microbiology, 2013
Fusarium infections are important problem worldwide, cause a broad spectrum of infections in human including superficial infections as well as locally invasive and disseminated infections.
Shailpreet Sidhu   +2 more
doaj   +1 more source

A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model

open access: yesScientific Reports, 2017
Zika virus (ZIKV) is a mosquito-borne flavivirus that has rapidly extended its geographic range around the world. Its association with abnormal fetal brain development, sexual transmission, and lack of a preventive vaccine have constituted a global ...
A. Brault   +10 more
semanticscholar   +1 more source

Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang   +10 more
wiley   +1 more source

Rare Coinfection of Scrub Typhus and Malaria in Immunocompetent Person [PDF]

open access: yes, 2012
Scrub Typhus, or tsutsugamushi disease is a febrile illness caused by bacteria of the family Rickettsiaceae and named Orientia tsutsugamushi. Recently it has been found to endemic in Subhimalayan region of India.Malaria is highly endemic in rest of India
Bellad, A   +5 more
core   +1 more source

Mouse papillomavirus infection persists in mucosal tissues of an immunocompetent mouse strain and progresses to cancer

open access: yesScientific Reports, 2017
Mouse papillomavirus has shown broad tissue tropism in nude mice. Previous studies have tested cutaneous infections in different immunocompromised and immunocompetent mouse strains.
N. Cladel   +7 more
semanticscholar   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease [PDF]

open access: yesPerspectives In Medical Research, 2018
Tuberculosis is one of the most prevalent bacterial infection in developing country like india and it is capable of affecting almost every system in the human body. Multifocal skeletal tuberculosis is a rare condition.
Majed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M4
doaj  

Visceral basidiobolomycosis: An overlooked infection in immunocompetent children

open access: yesAfrican Journal of Paediatric Surgery, 2015
Visceral basidiobolomycosis is an unusual fungal infection of viscera caused by saprophyte Basidiobolus ranarum. It is very rare in healthy children and poses a diagnostic challenge due to the non-specific clinical presentation and the absence of ...
Parkash Mandhan   +3 more
doaj   +1 more source

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