Results 141 to 150 of about 231,766 (309)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Oseltamivir-Resistant Pandemic (H1N1) 2009 in Patient with Impaired Immune System

Emerging Infectious Diseases, 2010
Grant A. Hill-Cawthorne, Silke Schelenz, Matthew Lawes, Samir Dervisevic   +3 more
doaj   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Investigation of Specific IgG‐Secreting Cells in Congenital Toxoplasmosis: The TOXODIAG Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study addressed the difficulty of establishing a postnatal biological diagnosis of congenital toxoplasmosis, particularly in the absence of toxoplasmosis monitoring during pregnancy, as is the case in many countries. Our work presents an ELISPOT (Enzyme‐Linked Immunospot) method adapted for the detection of B lymphocytes primed to produce IgG ...
F. Migot‐Nabias, N. Beldjoudi, K. Bailly, M. Andrieu, M. Surenaud, K. Gbedande, C. Couffignal, L. Mandelbrot, H. Yera, S. Houzé, M. Dambrun, TOXODIAG Study Group, E. Akrich, O. Anselem, S. Bani, A. Benbara, J. Colombe, A.‐M. Darras, L. Dubois, N. Ettalhaoui, H. Jabbarian, J.‐M. Jouannic, S. Le Levier, S. Letrou, P. Maurice, A. Oubahim, D. Oultache, J. Sibiude, M. Valentin   +28 more
wiley   +1 more source

Improving Linkage to the HCV Care Cascade in Nonspecialist Settings: Evaluation of the Performance and Triage Utility of the Elecsys HCV Duo Assay in Japan

Journal of Clinical Laboratory Analysis, EarlyView.
In nonspecialist departments, most anti‐HCV–positive individuals do not proceed to RNA testing. The Elecsys HCV Duo assay simultaneously detects anti‐HCV antibodies and core antigen from a single blood draw and preferentially identifies patients with clinically meaningful viral loads.
Hiroko Setoyama, Takehisa Watanabe, Shiho Miyase, Masakuni Tateyama, Motohiko Tanaka, Nobuhiro Minami, Masato Sasaki, Shunpei Hashigo, Kotaro Fukubayashi, Shotaro Ishii, Mutsuo Koga, Ryo Ichikawa, Hirofumi Iwashita, Yoshinari Sakai, Toshihiko Motohara, Kohei Tomita, Akinori Nakata, Yutaka Kai, Takeyasu Kounoe, Katsuki Haraoka, Takako Inoue, Takanori Suzuki, Kentaro Matsuura, Yasuhito Tanaka   +23 more
wiley   +1 more source

Immunocompromised [PDF]

, 2020
openaire   +1 more source

Chagas Disease in Immunocompromised Patients

As Chagas disease remains prevalent in the Americas, it is important that healthcare professionals and researchers are aware of the screening, diagnosis, monitoring, and treatment recommendations for the populations of patients they care for and study ...
Bern, Caryn, Clark, Eva H, Whitman, Jeffrey D, Messenger, Louisa A   +3 more
core   +1 more source

Maternal influenza vaccination during pregnancy and risk of autism spectrum disorder in the offspring

JCPP Advances, EarlyView.
Abstract Background Vaccination has been proposed as a potential risk factor for autism spectrum disorder (ASD), contributing to public hesitancy and mistrust toward immunization. Influenza vaccination during pregnancy is considered safe and effective in preventing serious maternal complications and adverse birth outcomes associated with influenza ...
Shahar Neeman, Maor Hemo, Gal Meiri, Dorit Shmueli, Idan Menashe   +4 more
wiley   +1 more source

Incidence, contributing factors, and predictors of diagnostic errors in medical inpatients: A retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx, Elena Hofmann, Martin Perrig, Gurpreet Dhaliwal, Wolf Hautz, Jörg P. Isenegger, Ernst Lipp, Drahomir Aujesky, Manuel R. Blum, Tobias Tritschler   +9 more
wiley   +1 more source

Editorial: Immune intervention avenues to control fungal infections in immunocompromised individuals

Frontiers in Immunology, 2023
Som G. Nanjappa
doaj   +1 more source