Results 151 to 160 of about 249,445 (302)

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source

The epidemiological impact and effectiveness of herpes zoster vaccination among older and pharmacologically immunocompromised adults: a population-based observational study. [PDF]

Lancet Reg Health West Pac
Reekie J, Stepien S, Li-Kim-Moy J, Simpson A, Macartney K, Liu B.   +5 more
europepmc   +1 more source

Enterovirus infections in children

Pediatric Investigation, EarlyView.
Enteroviruses (EVs) are major pathogens causing a wide spectrum of diseases in children worldwide. This review summarizes the epidemiology, virology, viral replication, and virus‐host interactions of EVs. It also highlights current advances in clinical diagnosis, antiviral therapies, and vaccine development, providing insights into future strategies ...
Xiangpeng Chen, Lingyun Guo, Xiaobo Lei, Linqing Zhao, Mingyan Hei, Jun Shen, Ju Yin, Fei Li, Jikui Deng, Gang Liu, Yong Zhang, Zhengde Xie   +11 more
wiley   +1 more source

Cytomegalovirus in Bronchoalveolar Lavage Fluid: A Predictor of Outcome in Immunocompromised Patients. [PDF]

J Med Virol
Zouvani T, Karakioulaki M, Jahn K, Fähndrich S, Frye BC, Grize L, Papakonstantinou E, Hengel H, Leuzinger K, Hirsch HH, Stolz D.   +10 more
europepmc   +1 more source

Beyond the traveller: immunocompromised residents as a blind spot in the South American yellow fever resurgence. [PDF]

New Microbes New Infect
Faico-Filho KS.
europepmc   +1 more source

An Occult Odontogenic Infection Behind a Persistent Left Chin Nodule

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yi‐Shan Teng, Huei‐Jing Wang, Shih‐Tsung Cheng   +2 more
wiley   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Cranial Subdural Empyema Due to <i>Citrobacter koseri</i> in a 96-Year-Old Immunocompromised Patient: Case Report. [PDF]

Case Rep Surg
Malesevic-Lepir M, Mohamed MMA, Binali S, Piotrowski A, Voellger B.   +4 more
europepmc   +1 more source

A Hitchhiker’s Guide to the BK Galaxy

Transplant International
Hans H. Hirsch, Camille N. Kotton
doaj   +1 more source

Risk of septic arthritis following corticosteroid and platelet‐rich plasma injections: A multicenter retrospective review

PM&R, EarlyView.
Abstract Background Platelet‐rich plasma injections (PRPI) are a relatively new and evolving treatment option for a variety of musculoskeletal injuries. It has been theorized that there is an increased risk of septic arthritis (SA) with PRPI, though there have been no dedicated studies to assess the incidence of SA and only three cases have been ...
Kory Ford, James Frazier, Anthony Beutler, Catherine Fairgrieve Appel, Daniel M. Cushman   +4 more
wiley   +1 more source