Results 191 to 200 of about 249,445 (302)

Efficacy and Safety of Abatacept Versus Placebo During Peanut Oral Immunotherapy for Adults With Severe Peanut Allergy

Allergy, EarlyView.
In this Phase 2a trial, severely peanut‐allergic participants were randomized to abatacept versus placebo with peanut oral immunotherapy (OIT) for 24 weeks, followed by 12 weeks of OIT alone. No significant difference was observed for the primary efficacy outcome (the relative change from baseline in peanut‐specific/total IgE ratio at 24 weeks), but ...
Marie‐Lee Simard, Camille Braun, Éloise Antony, Émilie Roy, Marie‐Ève Gingras, François Graham, Anne Des Roches, Louis Paradis, Kathryn Samaan, Florence Gingras‐Lessard, Roxane Labrosse, Thomas Eiwegger, Philippe Bégin   +12 more
wiley   +1 more source

COVID-19 vaccine effectiveness against in-hospital mortality in immunocompromised older adults: a Brazilian hospital surveillance study, 2024. [PDF]

Rev Bras Epidemiol
Rezende RPV, Pimentel JFN, Caxias BS, Salgueiro CM, Oliveira LT, Santos LFA, Pessanha CP, Tracierra VX, Simão MG, Pacheco MGA, Cruz VA, Oliveira LEDC.   +11 more
europepmc   +1 more source

Vaccination of immunocompromised hosts

, 2013
openaire   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Efficacy and Safety of Pritelivir vs Foscarnet for the Treatment of Acyclovir-Refractory Herpes Simplex Virus Infection in Immunocompromised Adults: A Randomized, Open-Label Phase 2 Trial. [PDF]

Open Forum Infect Dis
Kotton CN, Workowski KA, Kumar PN, Avery RK, Chemaly RF, Issa NC, Ramgopal M, Schiffer JT, Albrecht J, O'Neal HR, Chandrasekar P, Schreibman TS, Ramesh M, Ison MG, Sumner ME, Dane A, Surujbally B, Timmler B, Rangaraju M, Papanicolaou GA, Birkmann A, Wald A.   +21 more
europepmc   +1 more source

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Lise Kristensen, Anders Ivarsen   +6 more
wiley   +1 more source

Campylobacter jejuni as a Rare Pathogen in CIED Pocket Infections: A Case Report and Literature Review. [PDF]

Am J Case Rep
Barańska-Pawełczak K, Ziaja B, Opara M, Jacheć W.   +3 more
europepmc   +1 more source

Ocular and cutaneous infection due to Curvularia pseudobrachyspora in an immunosuppressed dog: Case report and in vitro antimycotic susceptibilities

Australian Veterinary Journal, EarlyView.
A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa, R Clark, J Granados‐Soler, C Palmieri, V Gonzalez‐Astudillo   +4 more
wiley   +1 more source

Lymphopenia is Associated with Altered Pathogen Distribution and Increased Disease Severity in Viral Pneumonia: A Multicenter Retrospective Cohort Study. [PDF]

Infect Drug Resist
Wu Y, Zhang X, Yang L, Su N, Li L.
europepmc   +1 more source

Prognostic impact of blood Epstein–Barr virus‐DNA in patients with peripheral T‐cell lymphoma, not otherwise specified

British Journal of Haematology, EarlyView.
Summary Peripheral T‐cell lymphoma, not otherwise specified (PTCL‐NOS), is a heterogeneous nodal T‐ and natural killer (NK)‐cell lymphoma with limited prognostic biomarkers. A subset of PTCL‐NOS characterized by Epstein–Barr virus (EBV) involvement in tumour cells has recently been recognized as EBV‐positive nodal T‐ and NK‐cell lymphoma (EBV+ nPTCL ...
Hyunseok Yoon, Hyungwoo Cho, In Hye Song, Sejin Kim, So Heun Lee, Kyoungmin Lee, Shin Kim, Chan‐Sik Park, Eun Jin Chae, Kyung Won Kim, Jin‐Sook Ryu, Sang‐Wook Lee, Jaewon Hyung, Heounjeong Go, Dok Hyun Yoon   +14 more
wiley   +1 more source