Results 201 to 210 of about 308,273 (316)

Type I and II Interferons Drive Abacavir Hypersensitivity via Treg Suppression and T‐Cell Enhancement in Immunocompetent HLA‐Transgenic Mice

Allergy, EarlyView.
Upregulated HLA‐B*57:01 expression in Tg/KO mice amplifies abacavir‐specific CD8+ T‐cell activation, driven by enhanced antigen presentation. Abacavir treatment induces robust pDC expansion and IFN‐α production, which selectively suppresses memory Treg populations.
SuJin Hwang, Telly Sepahpour, Stephanie Kortchak, Kirthiram Krishnaveni Sivakumar, Spyros Karaiskos, Ngoc Pham, Yura Jang, Montserrat Puig, Michael Norcross   +8 more
wiley   +1 more source

Pseudomonas aeruginosa: A Rare Cause of Necrotizing Fasciitis. [PDF]

Cureus
Kogulan CS, Ajibola O.
europepmc   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Aggressive Recurrent Bilateral Chylothorax Secondary to Follicular Lymphoma in an HIV-Positive Patient: A Case Report and Clinical Implications. [PDF]

Cureus
Jagra AS, Ali R, Klukowicz A, Sharma HO, Miller R.   +4 more
europepmc   +1 more source

Changing Aetiology of Perforated Peptic Ulcers: Rising Impact of Non‐Steroidal‐Anti‐Inflammatories in Western Australia

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Peptic ulcer disease (PUD) continues to be a health issue, mainly due to Helicobacter pylori (H. pylori) infection and non‐steroidal anti‐inflammatory drugs (NSAIDs). Despite better treatment of H. pylori and use of proton pump inhibitors, the rate of reduction in PUD complications is slowing down.
Vidya Willis, Tamalee Wilson, David R. Fletcher, Amanda J. Foster   +3 more
wiley   +1 more source

Disseminated <i>Nocardia paucivorans</i> infection in a 64-year-old patient with first manifestation as an ulnocarpal forearm lesion. [PDF]

Case Reports Plast Surg Hand Surg
Mohos P, Mathys L, Bratschi C, Claas GJ, Honigmann P, Keller M.   +5 more
europepmc   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Evidence of West Nile virus exposure in healthy donors and a clinical case in an immunocompromised child: emerging public health implications. [PDF]

Front Med (Lausanne)
Al-Nazawi AM, Alghamdi R, Al-Zahrani AA, Hetany WA, Khan M.   +4 more
europepmc   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

Acta Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source