Results 11 to 20 of about 89,131 (302)

Human immunodeficiency virus in Saudi Arabia: Current and future challenges

open access: yesJournal of Infection and Public Health, 2023
Introduction: Understanding the pathophysiology of HIV infection has been crucial to the design of effective anti-viral strategies. HIV infection is declining worldwide due to early diagnosis and the effective long-term use of anti-retroviral therapy ...
Maha Al-Mozaini   +7 more
doaj   +1 more source

HIV-2 Vpx neutralizes host restriction factor SAMHD1 to promote viral pathogenesis

open access: yesScientific Reports, 2021
SAMHD1, a human host factor found in myeloid cells which restricts HIV-1 replication. It depletes the dNTPs pool for viral cDNA syntheses, thus preventing the viral replication in the cells.
Ahlam Mohamed   +7 more
doaj   +1 more source

Implementation of a Routine Screening Program for Latent Tuberculosis Infection among Patients with Acute Leukemia at a Canadian Cancer Center

open access: yesCurrent Oncology, 2022
Background: Screening for latent tuberculosis infection (LTBI) in patients with hematological malignancy is recommended because of their increased risk of tuberculosis (TB). We assessed the utility of tuberculin skin test (TST) screening in patients with
Rbab Taha   +6 more
doaj   +1 more source

Evaluation of two molecular detection platforms for gastroenteritis pathogens in treated sewage water in the Eastern province of Saudi Arabia

open access: yesScientific Reports, 2022
The ability to screen environmental water samples for gastroenteritis pathogens, particularly viruses remains challenging. Here, we investigated the presence of enteric viruses in treated sewage effluent water samples collected from a cooling tower in ...
Fawaz A. Al-Wohaib   +5 more
doaj   +1 more source

Quantitative proteomics analysis reveals unique but overlapping protein signatures in HIV infections

open access: yesJournal of Infection and Public Health, 2021
Background: Human immunodeficiency virus-1 (HIV-1) exploits human host factors to complete its life cycle. Hence, discovery of HIV-regulated host proteins markers would better our understanding of the virus life-cycle and its contribution to pathogenesis
Maha Al-Mozaini   +7 more
doaj   +1 more source

New Insights on CMV Management in Solid Organ Transplant Patients: Prevention, Treatment, and Management of Resistant/Refractory Disease

open access: yesInfectious Diseases and Therapy, 2022
Cytomegalovirus (CMV) infection can have both direct and indirect effects after solid-organ transplantation, with a significant impact on transplant outcomes.
Camille Nelson Kotton, Nassim Kamar
doaj   +1 more source

Sporotrichosis In Immunocompromised Hosts [PDF]

open access: yesJournal of Fungi, 2019
Sporotrichosis is a global implantation or subcutaneous mycosis caused by several members of the genus Sporothrix, a thermo-dimorphic fungus. This disease may also depict an endemic profile, especially in tropical to subtropical zones around the world.
Flavio Queiroz-Telles   +2 more
openaire   +3 more sources

A diagnostically challenging case of pyelonephritis caused by Lactobacillus

open access: yesClinical Case Reports, 2022
Extracellular polysaccharides produced by Lactobacillus have been shown to stimulate the immune system, suppress reactivity to allergens, and protect from infections; these properties underlie the use of Lactobacillus in probiotic formulations and in the
Erika Hori   +2 more
doaj   +1 more source

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