Results 231 to 240 of about 89,131 (302)

Disseminated Invasive Aspergillosis in a Young Patient With Chronic Alcohol Use and Seemingly Preserved Immunocompetence: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Invasive aspergillosis, though typically seen in immunocompromised patients, can also affect immunocompetent individuals and mimic pulmonary malignancy. This case highlights the importance of considering fungal infections in the differential diagnosis of chronic respiratory symptoms, particularly in patients with risk factors such as heavy ...
Kumail Khandwala, Hiba Sawliha Syed, Shayan Sirat Maheen Anwar, Sehar Suleman, Khabab Abbasher Hussien Mohamed Ahmed   +4 more
wiley   +1 more source

Extensive Intra-host evolution and T cell escape by SARS-CoV-2 in a 2.5-year persistent infection of an immunocompromised host

Guerra-Assunção JA, McErlean R, Townsend K, Flaxl LM, Tian SJ, Swadling L, Breuer J, Lowe DM.   +7 more
europepmc   +1 more source

A Case Report on Disseminated Mycobacterium avium Complex Infection in an Otherwise Healthy Individual—A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Disseminated Mycobacterium avium complex (MAC) infection can mimic tuberculosis (TB) in immunocompetent individuals, leading to diagnostic and therapeutic challenges. Clinicians should consider nontuberculous mycobacteria (NTM) in patients unresponsive to anti‐tubercular therapy (ATT), especially in endemic regions.
Abdulla Bin Hridoy, Shadman Newaz, Moontasir Ahmed, Jannat Ara Tina, Supritom Sarker, Anika Tabassum, Mohammad Zakaria Al‐Aziz, Md. Robed Amin   +7 more
wiley   +1 more source

Why a Mycobacterium Avium Infected Patient Showed a Positive Xpert MTB/RIF Result?

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT This article discusses whether a MAC infected patient with a positive Xpert MTB/RIF test has a co‐infection with Mycobacterium tuberculosis (MTB). The patient presented with chronic, indolent pulmonary patchy shadows on imaging but lacked typical symptoms. The MTB antigen‐specific interferon‐gamma enzyme‐linked immunospot assay (T‐SPOT.TB) was
Lei Chen, Min Tang, Qin Wang, Hongni Jiang   +3 more
wiley   +1 more source

Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug‐Resistant Infections

Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate its mechanism of action via ergosterol biosynthesis inhibition and cell wall disruption ...
Maribasappa Karched, Mohammad Irshad, Jawad M. Behbehani   +2 more
wiley   +1 more source

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

Glia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu, Fang Jiang, Xinjie Liu, Ling Li, Ruimei Hu, Meng Dong, Aihua Cao   +6 more
wiley   +1 more source

Acute Toxicity and Genotoxicity of cMoL, a Lectin From Moringa oleifera Seeds With Antifungal Activity Against Cryptococcus Strains

Journal of Applied Toxicology, Volume 46, Issue 2, Page 682-696, February 2026.
ABSTRACT Coagulant Moringa oleifera lectin (cMoL) is one of the compounds involved in the application of M. oleifera seeds for traditional water treatment methods. The present study highlights the new biotechnological potential of cMoL lectin as an antifungal agent against Cryptococcus neoformans B3501 and H99 and Cryptococcus gattii R265 strains ...
Matheus Cavalcanti de Barros, Sávia Soraia Santana da Silva, Eduarda Pinto Gagliano, Alícia Natalie Silva dos Santos, Leydianne Leite de Siqueira Patriota, Gustavo Ramos Salles Ferreira, Pollyanna Michelle da Silva, Simone da Paz Leôncio Alves, Julliano Matheus de Lima Maux, Jacinto da Costa Silva Neto, Fernanda Rafaelly Nascimento de Santana, Fabiana Aparecida Cavalcante Silva, Marilene Henning Vainstein, Luana Cassandra Breitenbach Barroso Coelho, Thâmarah de Albuquerque Lima, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva   +16 more
wiley   +1 more source

Rhinovirus Infects B and CD4 T Lymphocytes in Hypertrophic Tonsils in Children

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Prolonged detection of rhinovirus (RV) in secretions after a typical cold and asymptomatic shedding are frequently reported. Although RV has been detected in human hypertrophic tonsils, its replicative status and host cell range remain unclear.
Ronaldo Martins, Flavia E. de Paula, Talita B. G. Mitchell, Miria F. Criado, Ricardo S. Cardoso, Bruna L. S. Jesus, Italo A. Castro, Murilo Henrique Anzolini Cassiano, Daniela Méria Ramos Rodrigues, Noilson Oliveira, Lucas Carenzi, Fabiana C. Valera, Edwin Tamashiro, Wilma T. Anselmo‐Lima, Eurico Arruda   +14 more
wiley   +1 more source

Beyond the Usual Suspects: RSV Infection in Patients With Hematological Malignancies Compared to Influenza and SARS‐COV‐2—A Report From the EPICOVIDEHA/EPIRESEHA Registry

American Journal of Hematology, Volume 101, Issue 2, Page 365-375, February 2026.
Jon Salmanton‐García, Francesco Marchesi, Milan Navrátil, Iker Falces‐Romero, Maria Ilaria Del Principe, Jorge Labrador, Klára Piukovics, Verena Petzer, Monika M. Biernat, Michail Samarkos, Dario Leotta, Nicola Fracchiolla, Anna Dąbrowska‐Iwanicka, Antonio Vena, Benjamín Víšek, Yavuz M. Bilgin, Jens Van Praet, Mario Virgilio Papa, Inmaculada Heras Fernando, Francesca Farina, Ľuboš Drgoňa, Josip Batinić, Barbora Weinbergerová, Nurettin Erben, Joanna Drozd‐Sokołowska, Patricia García‐Ramírez, Annarosa Cuccaro, Martin Čerňan, Nicola Sgherza, Tobias Lahmer, Donald C. Vinh, Gaëtan Plantefeve, Alberto López‐García, Chiara Cattaneo, Nikola Pantić, Sofya Khostelidi, Julio Dávila‐Valls, Andrés Soto‐Silva, László Imre Pinczés, Ferenc Magyari, Reham Abdelaziz Khedr, Michelina Dargenio, Martijn Bakker, Igor Stoma, Carolina Garcia‐Vidal, Ildefonso Espigado, Claudio Cerchione, Caterina Buquicchio, Zlate Stojanoski, Gabriele Magliano, Stefanie K. Gräfe, Avinash Aujayeb, Lucia Prezioso, Vladimir Otašević, Maria Merelli, Erica Mackenzie, Andreas Glenthøj, Eleni Gavriilaki, Noha Eisa, Mario Delia, Alessandro Busca, Ahlam Almasari, Tatjana Adžić‐Vukičević, Ivana Urošević, Uluhan Sili, Carolina Miranda‐Castillo, Gustavo‐Adolfo Méndez, Stef Meers, Monia Marchetti, Nicola Coppola, Gökçe Melis Çolak, Darko Antić, Ditte Stampe Hersby, Pellegrino Musto, Milche Cvetanoski, Martin Schönlein, Tommaso Francesco Aiello, Elena Arellano, Davide Nappi, Sonia Martín‐Pérez, Mirjana Mitrović, Raul Cordoba, Romane Prin, Marta Callejas‐Charavia, Gina Varricchio, Martina Bavastro, Alessandro Limongelli, Amalia N. Anastasopoulou, Alessandra Romano, Dominik Wolf, Kevin Nguyen, Lukas Van Den Ven, Alessia Di Pilla, Antonio Giordano, Oliver A. Cornely, Livio Pagano   +95 more
wiley   +1 more source

Cardio–Renal Diseases Are Independent Risk Factors of Severe Human Metapneumovirus Infection Among Patients Without Chronic Airway Diseases

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Human metapneumovirus (hMPV) causes mild and self‐limiting disease in adults. However, the risk factors for serious adverse outcomes following hMPV infection in adult patients without preexisting chronic airway diseases remain poorly understood.
Wang Chun Kwok, Isaac Sze Him Leung, Chun Ka Emmanuel Wong, James Chung Man Ho, David Chi Leung Lam, Mary Sau Man Ip, Shuk Man Ngai, Kelvin Kai Wang To, Desmond Yat Hin Yap   +8 more
wiley   +1 more source