Results 51 to 60 of about 1,275,927 (291)

Emerging Cutaneous Phaeohyphomycosis Caused by Alternaria infectoria

open access: yesActa Médica Portuguesa, 2021
Alternaria species belong to a group of opportunistic fungi that causes skin infection mainly in immunosuppressed patients. The authors describe two clinically distinct cases of cutaneous alternariosis caused by Alternaria infectoria in patients under ...
Katarína Kieselová   +3 more
doaj   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

open access: yesAdvanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang   +17 more
wiley   +1 more source

Infection in the immunocompromised host [Book Review]

open access: yes, 2019
Review of Oxford Specialist Handbook: Infection in the immunocompromised host Simon Fox, Brian Angus, Angela Minassian, Thomas Rowlinson Oxford University Press, 2018 pp 384, £39·99 ISBN 978 ...
Thomas, Mark
core   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

open access: yesAdvanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li   +19 more
wiley   +1 more source

First human infection caused by

open access: yesNew Microbes and New Infections
An 80-year-old man with diffuse large B-cell lymphoma developed pulmonary nocardiosis caused by Nocardia gipuzkoensis , with a concomitant central nervous system lesion. The isolate was identified as N. gipuzkoensis by secA1 gene sequencing.
Shiori Kitaya   +7 more
doaj   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

open access: yesAdvanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen   +17 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

open access: yes, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Critical Roles of O‐Acetylation Revealed by Synthetic Trisaccharide Antigens for a Broad‐Spectrum Anti‐Salmonella Vaccine

open access: yesAdvanced Science, EarlyView.
A synthetic glycoconjugate vaccine based on a diacetylated Salmonella trisaccharide elicits broadly protective antibodies against four major human pathogenic serovars. Mechanistic studies identify 2,3‐di‐O‐acetylation of rhamnose as a critical determinant of antigen recognition and breadth of protection, establishing a new strategy for broad‐spectrum ...
Xingling Pan   +7 more
wiley   +1 more source

La host (2014) Any XXVII. Núm. 22

open access: yes, 2014
Sumari: Història i Cultura.
Blasco, Miguel   +3 more
core   +1 more source

Cutaneous Manifestations of Infection in the Immunocompromised Host

open access: yes, 2012
The updated second edition  of Cutaneous Manifestations of Infection in the Immunocompromised Host is an invaluable reference for physicians and ancillary medical professionals involved in the care of patients with impaired immune systems due to cancer ...
Grossman, Marc E.   +3 more
core   +1 more source

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